DOLABELIDE-A AND DOLABELIDE-B, CYTOTOXIC-22-MEMBERED MACROLIDES ISOLATED FROM THE SEA HARE DOLABELLA-AURICULARIA

被引：51

作者：

OJIKA, M

NAGOYA, T

YAMADA, K

机构：

[1] Department of Chemistry, Faculty of Science, Nagoya University, Chikusa, Nagoya

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 41期

关键词：

D O I：

10.1016/0040-4039(95)01605-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new 22-membered macrolides, dolabelide A (1), and its deacetyl derivative, dolabelide B (2), have been isolated as cytotoxins from the Japanese sea hare Dolabella auricularia. The gross structures of 1 and 2 were determined by spectroscopic analysis, and their absolute stereochemistry was elucidated by a combination of chemical means and the NMR spectroscopic method.

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页码：7491 / 7494

页数：4

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