IMPORTANCE OF CONFORMATION OF TETRAHEDRAL INTERMEDIATE FOR ALPHA-CHYMOTRYPSIN-CATALYZED HYDROLYSIS OF PEPTIDE SUBSTRATES

被引：44

作者：

BIZZOZERO, SA ^{[1
]}

ZWEIFEL, BO ^{[1
]}

机构：

[1] ETH,LAB ORG CHEM,UNIVERSITATS STR 6,CH-8006 ZURICH,SWITZERLAND

来源：

FEBS LETTERS | 1975年 / 59卷 / 01期

关键词：

D O I：

10.1016/0014-5793(75)80351-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：105 / 108

页数：4

共 20 条

[1] KINETIC INVESTIGATION OF ALPHA-CHYMOTRYPSIN-CATALYZED HYDROLYSIS OF PEPTIDE SUBSTRATES - RELATIONSHIP BETWEEN PEPTIDE-STRUCTURE N-TERMINAL TO CLEAVED BOND AND REACTIVITY [J].

BAUMANN, WK ;

BIZZOZERO, SA ;

DUTLER, H .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 39 (02) :381-391

[2] SPECIFICITY OF ALPHA-CHYMOTRYPSIN - DIPEPTIDE SUBSTRATES [J].

BAUMANN, WK ;

BIZZOZERO, SA ;

DUTLER, H .

FEBS LETTERS, 1970, 8 (05) :257-+

[3] A NEW CONVENIENT REAGENT FOR PEPTIDE SYNTHESES [J].

BELLEAU, B ;

MALEK, G .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1968, 90 (06) :1651-&

[4] STRUCTURE OF CRYSTALLINE ALPHA-CHYMOTRYPSIN .5. ATOMIC STRUCTURE OF TOSYL-ALPHA-CHYMOTRYPSIN AT 2 A RESOLUTION [J].

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JOURNAL OF MOLECULAR BIOLOGY, 1972, 68 (02) :187-&

[5] NUMERICAL METHOD FOR ACQUISITION AND PROCESSING OF STEADY-STATE KINETIC DATA CONTAINED IN AN ENTIRE PROGRESSION CURVE - APPLICATION TO STUDY OF ALPHA-CHYMOTRYPSIN-CATALYZED HYDROLYSIS [J].

BIZZOZERO, SA ;

KAISER, AW ;

DUTLER, H .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 33 (02) :292-300

[6] CHYMOTRYPSIN CATALYSIS . EVIDENCE FOR A NEW INTERMEDIATE [J].

CAPLOW, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1969, 91 (13) :3639-&

[7] IMPORTANCE OF CONFORMATION OF TETRAHEDRAL INTERMEDIATE IN HYDROLYSIS OF ESTERS - SELECTIVE CLEAVAGE OF TETRAHEDRAL INTERMEDIATE CONTROLLED BY ORBITAL ORIENTATION [J].

DESLONGC.P ;

FREHEL, D ;

ATLANI, P ;

MALAVAL, A .

CANADIAN JOURNAL OF CHEMISTRY, 1972, 50 (20) :3405-&

[8] IMPORTANCE OF CONFORMATION OF TETRAHEDRAL INTERMEDIATE IN HYDROLYSIS OF AMIDES - SELECTIVE CLEAVAGE OF TETRAHEDRAL INTERMEDIATE CONTROLLED BY ORBITAL ORIENTATION [J].

DESLONGCHAMPS, P ;

LEBREUX, C ;

TAILLEFE.R .

CANADIAN JOURNAL OF CHEMISTRY, 1973, 51 (10) :1665-1669

[9] HYDROLYSIS OF CYCLIC ORTHOESTERS - STEREOELECTRONIC CONTROL IN CLEAVAGE OF HEMIORTHOESTER TETRAHEDRAL INTERMEDIATES [J].

DESLONGCHAMPS, P ;

CHENEVERT, R ;

TAILLEFER, RJ ;

MOREAU, C ;

SAUNDERS, JK .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1975, 53 (11) :1601-1615

[10] MECHANISM OF ALPHA-CHYMOTRYPSIN-CATALYZED HYDROLYSIS OF AMIDES - PH DEPENDENCE OF KC AND KM - KINETIC DETECTION OF AN INTERMEDIATE [J].

FERSHT, AR ;

REQUENA, Y .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1971, 93 (25) :7079-+

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