STEREOTAXIC RADIOTHERAPY OF IRREGULAR TARGETS - A COMPARISON BETWEEN STATIC CONFORMAL BEAMS AND NONCOPLANAR ARCS

被引:55
作者
LAING, RW
BENTLEY, RE
NAHUM, AE
WARRINGTON, AP
BRADA, M
机构
[1] ROYAL MARSDEN HOSP,ACAD UNIT RADIOTHERAPY & ONCOL,SUTTON SM2 5PT,SURREY,ENGLAND
[2] ROYAL MARSDEN HOSP,JOINT DEPT PHYS,SUTTON SM2 5PT,SURREY,ENGLAND
[3] INST CANC RES,JOINT DEPT PHYS,LONDON,ENGLAND
关键词
STEREOTAXIC RADIOTHERAPY; LINEAR ACCELERATOR; CONFORMAL BEAMS; DOSE-VOLUME DISTRIBUTION;
D O I
10.1016/0167-8140(93)90064-F
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Stereotactic radiotherapy using a linear accelerator is usually equated with the technique of delivery using multiple non-coplanar arcs, which achieves a spherical dose distribution. As the majority of intracranial lesions are not spherical, a range of schematized tumour shapes were planned to assess the role of static conformal beams in the treatment of irregular lesions. A sphere and 2 ellipsoids, ranging from 20 to 50 mm maximum diameter located intracranially were planned using 3, 4, and 6 non-coplanar static beams with conformal blocks and were compared with four 120-degrees non-coplanar arcs. Comparison of the plans was made by the relative sparing of normal tissue outside the target volume using three-dimensional dose-volume distributions. Non-coplanar arcs spared more normal tissue at low isodoses and achieved the best high dose sparing for spherical targets. For the majority of irregular targets, 3 and 4 static beams spared more tissue at doses greater-than-or-equal-to 50% and greater-than-or-equal-to 80% than the arc technique. For all irregular volumes, maximum sparing of normal tissue to isodoses greater-than-or-equal-to 50% and greater-than-or-equal-to 80% of the treatment isodose was obtained with 6 static conformal beams. We conclude that irregularly shaped tumours suitable for stereotactic radiotherapy with a linear accelerator are better treated with conformal static non-coplanar beams rather than with the multiple arc technique.
引用
收藏
页码:241 / 246
页数:6
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