SERONEGATIVE CHRONIC RELAPSING NEUROBORRELIOSIS

被引：36

作者：

LAWRENCE, C

LIPTON, RB

LOWY, FD

COYLE, PK

机构：

[1] SUNY STONY BROOK, DEPT NEUROL, STONY BROOK, NY 11794 USA

[2] SUNY STONY BROOK, DEPT MED, STONY BROOK, NY 11794 USA

[3] SUNY STONY BROOK, ALBERT EINSTEIN COLL MED, DIV INFECT DIS, STONY BROOK, NY 11794 USA

来源：

EUROPEAN NEUROLOGY | 1995年 / 35卷 / 02期

关键词：

LYME DISEASE; SERONEGATIVE; IMMUNE COMPLEX; HERXHEIMER;

D O I：

10.1159/000117104

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report an unusual patient with evidence of Borrelia burgdorferi infection who experienced repeated neurologic relapses despite aggressive antibiotic therapy. Each course of therapy was associated with a Jarisch-Herxheimer-like reaction. Although the patient never had detectable free antibodies to B. burgdorferi in serum or spinal fluid, the CSF was positive on multiple occasions for complexed anti-B. burgdorferi antibodies, B. burgdorferi nucleic acids and free antigen.

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页码：113 / 117

页数：5

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