STUDIES DIRECTED TOWARD ASCERTAINING THE ACTIVE CONFORMATION OF 1,4-DIHYDROPYRIDINE CALCIUM ENTRY BLOCKERS

被引：60

作者：

ROVNYAK, G

ANDERSEN, N

GOUGOUTAS, J

HEDBERG, A

KIMBALL, SD

MALLEY, M

MORELAND, S

PORUBCAN, M

PUDZIANOWSKI, A

机构：

[1] SQUIBB INST MED RES,DEPT MOLEC MODELLING X-RAY CRYSTALLOG,PRINCETON,NJ 08543

[2] SQUIBB INST MED RES,DEPT PHARMACOL,PRINCETON,NJ 08543

[3] UNIV WASHINGTON,DEPT CHEM,SEATTLE,WA 98195

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 05期

关键词：

D O I：

10.1021/jm00400a008

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：936 / 944

页数：9

共 46 条

[1] SELECTIVE INVERSION RECOVERY DELTA-NOE SPECTROSCOPY WITH TRUNCATED RELAXATION DELAYS .1. TECHNIQUES FOR MINIMIZING SPIN DIFFUSION IN STUDIES OF PROTEIN-BOUND CONFORMATIONS OF SMALL MOLECULES [J].

ANDERSEN, NH ;

NGUYEN, KT ;

EATON, HL .

JOURNAL OF MAGNETIC RESONANCE, 1985, 63 (02) :365-375

[2] RAPID ACQUISITION OF NOE DIFFERENCE SPECTRA - THE RELATIVE MERITS OF TRANSIENT VERSUS DRIVEN EXPERIMENTAL PROTOCOLS [J].

ANDERSEN, NH ;

NGUYEN, KT ;

HARTZELL, CJ ;

EATON, HL .

JOURNAL OF MAGNETIC RESONANCE, 1987, 74 (02) :195-211

[3] DIETHYL 3,6-DIHYDRO-2,4-DIMETHYL-2,6-METHANO-1,3-BENZOTHIAZOCINE-5,11-DICARBOXYLATES AS CALCIUM ENTRY ANTAGONISTS - NEW CONFORMATIONALLY RESTRAINED ANALOGS OF HANTZSCH 1,4-DIHYDROPYRIDINES RELATED TO NITRENDIPINE AS PROBES FOR RECEPTOR-SITE CONFORMATIONE [J].

BALDWIN, JJ ;

CLAREMON, DA ;

LUMMA, PK ;

MCCLURE, DE ;

ROSENTHAL, SA ;

WINQUIST, RJ ;

FAISON, EP ;

KACZOROWSKI, GJ ;

TRUMBLE, MJ ;

SMITH, GM .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (04) :690-695

[4]

BELLEMANN P, 1981, ARZNEIMITTEL-FORSCH, V31-2, P2064

[5]

BERNTSSON P, 1981, ACTA PHARM SUEC, V18, P221

[6] HIGH-AFFINITY BINDING OF A CALCIUM-CHANNEL ANTAGONIST TO SMOOTH AND CARDIAC-MUSCLE [J].

BOLGER, GT ;

GENGO, PJ ;

LUCHOWSKI, EM ;

SIEGEL, H ;

TRIGGLE, DJ ;

JANIS, RA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1982, 104 (04) :1604-1609

[7]

BOLGER GT, 1983, J PHARMACOL EXP THER, V225, P291

[8] 4-ARYLDIHYDROPYRIDINES, A NEW CLASS OF HIGHLY-ACTIVE CALCIUM-ANTAGONISTS [J].

BOSSERT, F ;

MEYER, H ;

WEHINGER, E .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1981, 20 (09) :762-769

[9]

BOSSERT F, 1979, ARZNEIMITTEL-FORSCH, V29-1, P226

[10]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

← 1 2 3 4 5 →