MAGNETIC MANIPULATION INSTRUMENTATION FOR MEDICAL PHYSICS RESEARCH

被引:96
作者
GILLIES, GT
RITTER, RC
BROADDUS, WC
GRADY, MS
HOWARD, MA
MCNEIL, RG
机构
[1] UNIV VIRGINIA, DEPT PHYS, JW BEAMS LAB PHYS, CHARLOTTESVILLE, VA 22901 USA
[2] VIRGINIA COMMONWEALTH UNIV, MED COLL VIRGINIA, DIV NEUROSURG, MCV STN, RICHMOND, VA 23298 USA
[3] UNIV WASHINGTON, HARBORVIEW MED CTR, DEPT NEUROL SURG, SEATTLE, WA 98104 USA
[4] UNIV IOWA HOSP & CLIN, DIV NEUROSURG, IOWA CITY, IA 52242 USA
[5] STEREOTAXIS INC, MENLO PK, CA 94025 USA
关键词
D O I
10.1063/1.1145242
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
The noncontact magnetic manipulation of probe masses within the body is an area of research that has received substantial attention from the medical physics community, especially during the past three decades. The therapeutic and diagnostic possibilities arising from such technology include site-specific drug delivery within the central nervous system, advancement of techniques for navigation and selective catheterization of vessels within the cardiovascular and cerebrovascular systems, and the nonsurgical exploration of the alimentary and respiratory tracts. In this review, we examine the physical principles underlying in vivo magnetic manipulation systems, and catalog the various types of instrumentation used for such purposes to date. Thereafter, we evaluate the different methods of image-based localization used to identify the position of the probe within the body. Finally, we appraise an emerging technology known as nonlinear magnetic stereotaxis, a technique that permits minimally invasive access to difficult-to-approach parts of the brain. We close the review with a few comments on the directions for future work within this field.
引用
收藏
页码:533 / 562
页数:30
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