INVITRO EVALUATION OF DERMAL PRODRUG DELIVERY - TRANSPORT AND BIOCONVERSION OF A SERIES OF ALIPHATIC ESTERS OF METRONIDAZOLE

被引：32

作者：

JOHANSEN, M

MOLLGAARD, B

WOTTON, PK

LARSEN, C

HOELGAARD, A

机构：

[1] ROYAL DANISH SCH PHARM, DEPT PHARMACEUT, 2 UNIVERSITETSPARKEN, DK-2100 COPENHAGEN, DENMARK

[2] UNIV NOTTINGHAM, DEPT PHARM, NOTTINGHAM NG7 2RD, ENGLAND

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1986年 / 32卷 / 2-3期

关键词：

D O I：

10.1016/0378-5173(86)90179-1

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：199 / 206

页数：8

共 22 条

[1] INVITRO BIOTRANSFORMATION OF GLUCOCORTICOIDS IN LIVER AND SKIN HOMOGENATE FRACTION FROM MAN, RAT AND HAIRLESS MOUSE
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[2] SKIN STRUCTURE AND METABOLISM - RELEVANCE TO THE DESIGN OF CUTANEOUS THERAPEUTICS
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[J]. PHARMACEUTICAL RESEARCH, 1984, (04) : 148 - 153
[3] LEACHING OF HYDROLYTIC ENZYMES FROM HUMAN-SKIN IN CUTANEOUS PERMEATION STUDIES AS DETERMINED WITH METRONIDAZOLE AND 5-FLUOROURACIL PRO-DRUGS
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[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1983, 15 (03) : 285 - 292
[4] ENHANCED DELIVERY OF MITOMYCIN-C DERIVATIVES THROUGH HAIRLESS MOUSE AND RAT SKINS
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MUKAI, E
KIMURA, T
SEZAKI, H
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1985, 37 (08) : 542 - 544
[5] A COMPARISON OF THE CHEMICAL-STABILITY AND THE ENZYMATIC-HYDROLYSIS OF A SERIES OF ALIPHATIC AND AROMATIC ESTER DERIVATIVES OF METRONIDAZOLE
JOHANSEN, M
LARSEN, C
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1985, 26 (03) : 227 - 241
[6] KATZ M, 1971, HDB EXPT PHARM, P105
[7] IMPROVED DELIVERY THROUGH BIOLOGICAL-MEMBRANES .9. KINETICS AND MECHANISM OF HYDROLYSIS OF METHYLSULFINYLMETHYL 2-ACETOXYBENZOATE AND RELATED ASPIRIN PRODRUGS
LOFTSSON, T
BODOR, N
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1981, 70 (07) : 750 - 755
[8] PRO-DRUGS AS DRUG DELIVERY SYSTEMS .23. IMPROVED DERMAL DELIVERY OF 5-FLUOROURACIL THROUGH HUMAN-SKIN VIA N-ACYLOXYMETHYL PRO-DRUG DERIVATIVES
MOLLGAARD, B
HOELGAARD, A
BUNDGAARD, H
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1982, 12 (2-3) : 153 - 162
[9] MOLLGAARD B, 1983, ACTA PHARM SUEC, V20, P433
[10] MOLLGAARD B, 1983, ACTA PHARM SUEC, V20, P443

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