BETA-GLUCOSIDASE ACTIVITY TOWARDS A BILE-ACID GLUCOSIDE IN HUMAN LIVER

被引：17

作者：

MATERN, H ^{[1
]}

GARTZEN, R ^{[1
]}

MATERN, S ^{[1
]}

机构：

[1] RHEIN WESTFAL TH AACHEN,DEPT INTERNAL MED 3,W-5100 AACHEN,GERMANY

来源：

FEBS LETTERS | 1992年 / 314卷 / 02期

关键词：

BILE ACID; GLUCOSIDE; GLUCOSIDASE;

D O I：

10.1016/0014-5793(92)80970-R

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Human liver contains hydrolytic activity toward 3beta-glucosido-chenodeoxycholic acid. This beta-glucosidase activity, localized predominantly in the microsomal fraction, was optimally active in the presence of divalent metal ions close to pH 5.0 and was inhibited by EDTA. Kinetic parameters and other catalytic properties of hydrolytic activity towards 3beta-glucosido-chenodeoxycholic acid from human liver microsomes are described.

引用

页码：183 / 186

页数：4

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