EVIDENCE FOR NATURALLY-OCCURRING RECOMBINATION IN THE GENE ENCODING THE MAJOR OUTER-MEMBRANE PROTEIN OF LYMPHOGRANULOMA-VENEREUM ISOLATES OF CHLAMYDIA-TRACHOMATIS

被引：45

作者：

HAYES, LJ

YEARSLEY, P

TREHARNE, JD

BALLARD, RA

FEHLER, GH

WARD, ME

机构：

[1] UNIV LONDON,INST OPHTHALMOL,VIROL SECT,LONDON EC1V 9EL,ENGLAND

[2] UNIV WITWATERSRAND,S AFRICAN INST MED RES,DEPT MICROBIOL,STD RES UNIT,JOHANNESBURG 2000,SOUTH AFRICA

来源：

INFECTION AND IMMUNITY | 1994年 / 62卷 / 12期

关键词：

D O I：

10.1128/IAI.62.12.5659-5663.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The nucleotide sequence of the major outer membrane protein gene (omp1) was determined for three geographically distinct lymphogranuloma venereum isolates which were serologically untypeable. The three omp1 sequences were hybrids of serovars L1 and L2, containing a putative DNA recombination site in variable segment 2. Efforts to manipulate the chlamydial genome in vitro by recombination should be intensified.

引用

收藏

页码：5659 / 5663

页数：5

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