CORRELATION BETWEEN LEFT FRONTAL PHOSPHOLIPIDS AND WISCONSIN CARD SORT TEST-PERFORMANCE IN SCHIZOPHRENIA

被引：46

作者：

DEICKEN, RF

MERRIN, EL

FLOYD, TC

WEINER, MW

机构：

[1] VET AFFAIRS MED CTR,PSYCHIAT SERV,SAN FRANCISCO,CA 94121

[2] UNIV CALIF SAN FRANCISCO,DEPT PSYCHIAT,SAN FRANCISCO,CA 94143

[3] UNIV CALIF SAN FRANCISCO,DEPT MED,SAN FRANCISCO,CA 94143

[4] UNIV CALIF SAN FRANCISCO,DEPT RADIOL,SAN FRANCISCO,CA

来源：

SCHIZOPHRENIA RESEARCH | 1995年 / 14卷 / 02期

关键词：

MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHOLIPID; FRONTAL LOBE;

D O I：

10.1016/0920-9964(94)00036-8

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The relationship between frontal lobe phospholipid measures as measured by in vivo (31)phosphorus magnetic resonance spectroscopic imaging and performance on the Wisconsin Card Sort Test was examined in 16 chronic schizophrenic patients and 13 normal controls. Lower left frontal phosphomonoester levels in the schizophrenics were associated with fewer categories achieved, lower percent conceptual level, and greater total errors. No significant correlations between frontal phospholipid measures and performance on the WCST were noted in the controls. The results suggest a relationship between altered left frontal phospholipid metabolism and a specific measure, of frontal lobe neuropsychological functioning.

引用

页码：177 / 181

页数：5