HEMOLYSIS AND CHOLESTASIS FOLLOWING IMPLANTATION OF A TRANSJUGULAR INTRAHEPATIC PORTOSYSTEMIC SHUNT

被引:7
作者
CHENG, KH [1 ]
LAMERIS, JS [1 ]
DEMAN, RA [1 ]
PIETERMAN, H [1 ]
VANBUUREN, HR [1 ]
机构
[1] UNIV HOSP ROTTERDAM,DEPT HEPATOGASTROENTEROL,CA415,DR MOLEWATERPLEIN 40,3015 GD ROTTERDAM,NETHERLANDS
关键词
TRANSJUGULAR INTRAHEPATIC PORTOSYSTEMIC SHUNT; HEMOLYSIS; CHOLESTASIS; CIRRHOSIS; ASCITES;
D O I
10.1097/00042737-199408000-00020
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Objective: To report a case where a patient developed clinically overt haemolysis and cholestasis following implantation of a transjugular intrahepatic portosystemic shunt (TIPS). Patient: A 69-year-old man with posthepatic (B and C) cirrhosis and refractory ascites. Results: Immediate onset of marked cholestasis and haemolysis following TIPS implantation, with spontaneous gradual improvement. On follow-up 4 months later, however, evidence of mild haemolysis and cholestasis persisted. Conclusion: Haemolysis and cholestasis can complicate the insertion of a TIPS shunt. The cause of cholestasis observed in this patient is unclear. Haemolysis following TIPS implanation was probably caused by mechanical damage to the erythrocytes, related to local turbulent blood flow, and because the intravenous sections of the stent were not fully covered with endothelial cells.
引用
收藏
页码:749 / 751
页数:3
相关论文
共 13 条
[11]  
Longo J.M., Bilbao J.I., Rousseau H.P., Garcia-Villareal L., Vinel J.P., Zozaya J.M., Et al., Transjugular intrahepatic portosystemic shunt: Evaluation with doppler sonography, Radiology, 186, pp. 529-534, (1993)
[12]  
Sutera S.P., Mehrjardi M.H., Deformation and fragmentation of human red blood cells in turbulent shear flow, Biophys J, 15, pp. 1-10, (1975)
[13]  
Vinel J.P., Rousseau H., Bilbao J.L., Maquin P., Longo J.M., Garcia L., Et al., Transjugular intrahepatic portosystemic shunts using the wallstent endoprosthesis: Histological study in animals and in patients [abstract], J Hepatol, 16, (1992)