THE EPSTEIN-BARR-VIRUS NUCLEAR ANTIGEN LEADER PROTEIN ASSOCIATES WITH HSP72/HSC73

被引：40

作者：

MANNICK, JB

TONG, X

HEMNES, A

KIEFF, E

机构：

来源：

JOURNAL OF VIROLOGY | 1995年 / 69卷 / 12期

关键词：

D O I：

10.1128/JVI.69.12.8169-8172.1995

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Epstein-Barr virus nuclear antigen leader protein (EBNA-LP) is important for primary B-lymphocyte growth transformation. We now demonstrate that the W repeat-encoded domain of EBNA-LP significantly associates with proteins of the heat shock protein 70 family (hsp72/hsc73). hsp72/hsc73 may mediate the previously observed interaction between EBNA-LP and the retinoblastoma protein or p53.

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页码：8169 / 8172

页数：4

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