RETROVIRAL PROTEINASES - A 2ND FRONT AGAINST AIDS

被引：47

作者：

BLUNDELL, T ^{[1
]}

PEARL, L ^{[1
]}

机构：

[1] INST CANC RES,CELL & MOLEC BIOL SECT,VIROL LAB,LONDON SW3,ENGLAND

来源：

NATURE | 1989年 / 337卷 / 6208期

关键词：

D O I：

10.1038/337596a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：596 / 597

页数：2

共 16 条

[1] 18TH KREBS,HANS LECTURE - KNOWLEDGE-BASED PROTEIN MODELING AND DESIGN
BLUNDELL, T
CARNEY, D
GARDNER, S
HAYES, F
HOWLIN, B
HUBBARD, T
OVERINGTON, J
SINGH, DA
SIBANDA, BL
SUTCLIFFE, M
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1988, 172 (03): : 513 - 520
[2] ON THE RATIONAL DESIGN OF RENIN INHIBITORS - X-RAY STUDIES OF ASPARTIC PROTEINASES COMPLEXED WITH TRANSITION-STATE ANALOGS
BLUNDELL, TL
COOPER, J
FOUNDLING, SI
JONES, DM
ATRASH, B
SZELKE, M
[J]. BIOCHEMISTRY, 1987, 26 (18) : 5585 - 5590
[3] 3-DIMENSIONAL STRUCTURE OF THE COMPLEX OF THE RHIZOPUS-CHINENSIS CARBOXYL PROTEINASE AND PEPSTATIN AT 2.5-A RESOLUTION
BOTT, R
SUBRAMANIAN, E
DAVIES, DR
[J]. BIOCHEMISTRY, 1982, 21 (26) : 6956 - 6962
[4] EXPRESSION OF THE GAG-POL FUSION PROTEIN OF MOLONEY MURINE LEUKEMIA-VIRUS WITHOUT GAG PROTEIN DOES NOT INDUCE VIRION FORMATION OR PROTEOLYTIC PROCESSING
FELSENSTEIN, KM
GOFF, SP
[J]. JOURNAL OF VIROLOGY, 1988, 62 (06) : 2179 - 2182
[5] MOLECULAR-STRUCTURE OF AN ASPARTIC PROTEINASE ZYMOGEN, PORCINE PEPSINOGEN, AT 1.8 A RESOLUTION
JAMES, MNG
SIELECKI, AR
[J]. NATURE, 1986, 319 (6048) : 33 - 38
[6] CONFORMATIONAL FLEXIBILITY IN THE ACTIVE-SITES OF ASPARTYL PROTEINASES REVEALED BY A PEPSTATIN FRAGMENT BINDING TO PENICILLOPEPSIN
JAMES, MNG
SIELECKI, A
SALITURO, F
RICH, DH
HOFMANN, T
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (20): : 6137 - 6141
[7] STRUCTURE AND REFINEMENT OF PENICILLOPEPSIN AT 1.8-A RESOLUTION
JAMES, MNG
SIELECKI, AR
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1983, 163 (02) : 299 - 361
[8] INHIBITION OF RETROVIRAL PROTEASE ACTIVITY BY AN ASPARTYL PROTEINASE-INHIBITOR
KATOH, I
YASUNAGA, T
IKAWA, Y
YOSHINAKA, Y
[J]. NATURE, 1987, 329 (6140) : 654 - 656
[9] CRYSTAL-STRUCTURE OF A RETROVIRAL PROTEASE PROVES RELATIONSHIP TO ASPARTIC PROTEASE FAMILY
MILLER, M
JASKOLSKI, M
RAO, JKM
LEIS, J
WLODAWER, A
[J]. NATURE, 1989, 337 (6207) : 576 - 579
[10] 3-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1
NAVIA, MA
FITZGERALD, PMD
MCKEEVER, BM
LEU, CT
HEIMBACH, JC
HERBER, WK
SIGAL, IS
DARKE, PL
SPRINGER, JP
[J]. NATURE, 1989, 337 (6208) : 615 - 620

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