TRISOMY-2, TRISOMY-20, AND DEL(L7P) AS SOLE CHROMOSOMAL-ABNORMALITIES IN 3 CASES OF HEPATOBLASTOMA

被引：35

作者：

TONK, VS ^{[1
]}

WILSON, KS ^{[1
]}

TIMMONS, CF ^{[1
]}

SCHNEIDER, NR ^{[1
]}

机构：

[1] UNIV TEXAS,SW MED CTR,DEPT PATHOL,DALLAS,TX 75235

来源：

GENES CHROMOSOMES & CANCER | 1994年 / 11卷 / 03期

关键词：

D O I：

10.1002/gcc.2870110309

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Short-term cultures of three hepatoblastomas were analyzed cytogenetically. Trisomy 2, trisomy 20, and a deletion of 17p were found as the sole abnormalities, yielding the karyotypes 47,XY,+2; 47,XX,+20; and 46,XX,del(17)(p12)/46,XX. This is the first reported case of deletion of 17p as the sole chromosomal abnormality in a hepatoblastoma and the first reported case of trisomy 20 without double minute chromosomes as a sole chromosomal abnormality in hepatoblastoma. (C) 1994 Wiley-Liss, Inc.

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页码：199 / 202

页数：4

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