FACILE SYNTHESIS OF 1,4-BENZODIAZEPIN-5-ONE DERIVATIVES VIA INTRAMOLECULAR AZA-WITTIG REACTION - APPLICATION TO AN EFFICIENT SYNTHESIS OF O-BENZYL DC-81

被引：63

作者：

EGUCHI, S ^{[1
]}

YAMASHITA, K ^{[1
]}

MATSUSHITA, Y ^{[1
]}

KAKEHI, A ^{[1
]}

机构：

[1] SHINSHU UNIV,FAC ENGN,DEPT CHEM & MAT ENGN,WAKASATO,NAGANO 380,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1995年 / 60卷 / 13期

关键词：

D O I：

10.1021/jo00118a016

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The tandem Staudinger/aza-Wittig reaction of N-(o-azidobenzoyl)-alpha-amino acid esters gave the corresponding 1,4-benzodiazepin-5-one derivatives in moderate to good yields. This method was applied successfully to a new efficient synthesis of BzlDC-81.

引用

页码：4006 / 4012

页数：7

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