PHARMACOLOGY OF SMOOTH-MUSCLE CELL REPLICATION

被引：242

作者：

JACKSON, CL ^{[1
]}

SCHWARTZ, SM ^{[1
]}

机构：

[1] UNIV WASHINGTON, SCH MED, DEPT PATHOL, SEATTLE, WA 98195 USA

来源：

HYPERTENSION | 1992年 / 20卷 / 06期

关键词：

ATHEROSCLEROSIS; GROWTH SUBSTANCES; HYPERTENSION; ESSENTIAL; MUSCLE; SMOOTH; VASCULAR;

D O I：

10.1161/01.HYP.20.6.713

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

The suggestion that smooth muscle cell proliferation contributes to hypertension, atherosclerosis, and restenosis after angioplasty has led to a growing interest in the use of drugs to inhibit this process. This review summarizes pharmacological studies of smooth muscle cell proliferation in vitro and in vivo and identifies specific mediators of proliferation that are implicated by drugs binding with high affinity to enzymes or receptors.

引用

页码：713 / 736

页数：24

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