AB-INITIO DIRECT PHASING OF PROTEINS - THE LIMITS

被引：8

作者：

GIACOVAZZO, C

GUAGLIARDI, A

RAVELLI, R

SILIQI, D

机构：

[1] DEPT CRYSTAL & STRUCT CHEM,UTRECHT,NETHERLANDS

[2] DEPT INORGAN CHEM,TIRANE,ALBANIA

来源：

ZEITSCHRIFT FUR KRISTALLOGRAPHIE | 1994年 / 209卷 / 02期

关键词：

D O I：

10.1524/zkri.1994.209.2.136

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The role of directed methods in the protein field is analyzed. A criterion is formulated which suggests the necessary conditions for the success or the failure of the ab initio direct procedures. The distribution of quantity z = [alpha]/sigma(alpha) is central in our considerations. Most of the experimental protein data do not satisfy such a criterion, therefore their ab-initio solution is a quite improbable event.

引用

页码：136 / 142

页数：7

共 22 条

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