CELL-CYCLE TARGETS OF THE DNA TUMOR-VIRUSES

被引：92

作者：

NEVINS, JR

机构：

[1] Section of Genetics, Howard Hughes Medical Institute, Duke University Medical Center, Durham

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1994年 / 4卷 / 01期

关键词：

D O I：

10.1016/0959-437X(94)90101-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The realization that the cellular transcription factor E2F is a target for the action of the retinoblastoma tumor suppressor protein, as well as related regulatory proteins, and that this regulation is disrupted by oncogenic products of the DNA tumor viruses, has led to studies that have provided important insights into molecular mechanisms of cellular growth control.

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页码：130 / 134

页数：5

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