LOCALIZATION OF THE GENE ENCODING A TYPE-1 PROTEIN PHOSPHATASE CATALYTIC SUBUNIT TO HUMAN-CHROMOSOME BAND-11Q13

被引：82

作者：

BARKER, HM

JONES, TA

SILVA, EFD

SPURR, NK

SHEER, D

COHEN, PTW

机构：

[1] IMPERIAL CANC RES FUND,POTTERS BAR EN6 3LD,HERTS,ENGLAND

[2] IMPERIAL CANC RES FUND,LONDON WC2A 3PX,ENGLAND

来源：

GENOMICS | 1990年 / 7卷 / 02期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0888-7543(90)90536-4

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A cDNA encoding one isoform (PP1α) of the catalytic subunit of human protein phosphatase 1 has been isolated and used to map the human PP1α gene (PPP1A) to chromosome band 11q13 by analysis of somatic cell hybrids and in situ hybridization. Neoplasms that map to 11q13 are discussed in the light of the recent findings that PP1α is a putative tumor suppressor and that it plays a key role in the control of mitosis. © 1990.

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页码：159 / 166

页数：8

相关论文

共 45 条

[21] CHROMOSOMAL LOCALIZATION OF HUMAN CELLULAR HOMOLOGS OF 2 VIRAL ONCOGENES [J].

HEISTERKAMP, N ;

GROFFEN, J ;

STEPHENSON, JR ;

SPURR, NK ;

GOODFELLOW, PN ;

SOLOMON, E ;

CARRITT, B ;

BODMER, WF .

NATURE, 1982, 299 (5885) :747-749

[22] IDENTIFICATION OF MIC5, A HUMAN X-LINKED GENE CONTROLLING EXPRESSION OF A CELL-SURFACE ANTIGEN - DEFINITION BY A MONOCLONAL-ANTIBODY RAISED AGAINST A HUMAN X MOUSE SOMATIC-CELL HYBRID [J].

HOPE, RM ;

GOODFELLOW, PN ;

SOLOMON, E ;

BODMER, WF .

CYTOGENETICS AND CELL GENETICS, 1982, 33 (03) :204-212

[23] RELATIONSHIPS BETWEEN GENES ON HUMAN CHROMOSOME-11 ENCODING CELL-SURFACE ANTIGENS [J].

JONES, C ;

BILL, J ;

LARIZZA, L ;

PYM, B ;

GOODFELLOW, P ;

TUNNACLIFFE, A .

SOMATIC CELL AND MOLECULAR GENETICS, 1984, 10 (04) :423-428

[24] MUTATION AND CANCER - STATISTICAL STUDY OF RETINOBLASTOMA [J].

KNUDSON, AG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1971, 68 (04) :820-&

[25] MULTIPLE ENDOCRINE NEOPLASIA TYPE-1 GENE MAPS TO CHROMOSOME-11 AND IS LOST IN INSULINOMA [J].

LARSSON, C ;

SKOGSEID, B ;

OBERG, K ;

NAKAMURA, Y ;

NORDENSKJOLD, M .

NATURE, 1988, 332 (6159) :85-87

[26] HIGH-RESOLUTION CHROMOSOME SORTING AND DNA SPOT-BLOT ANALYSIS ASSIGN MCARDLES SYNDROME TO CHROMOSOME-11 [J].

LEBO, RV ;

GORIN, F ;

FLETTERICK, RJ ;

KAO, FT ;

CHEUNG, MC ;

BRUCE, BD ;

KAN, YW .

SCIENCE, 1984, 225 (4657) :57-59

[27]

Maniatis T., 1982, MOL CLONING

[28] IMPROVEMENT OF THE DIDEOXY CHAIN TERMINATION METHOD OF DNA SEQUENCING BY USE OF DEOXY-7-DEAZAGUANOSINE TRIPHOSPHATE IN PLACE OF DGTP [J].

MIZUSAWA, S ;

NISHIMURA, S ;

SEELA, F .

NUCLEIC ACIDS RESEARCH, 1986, 14 (03) :1319-1324

[29] THE FISSION YEAST DIS2+ GENE REQUIRED FOR CHROMOSOME DISJOINING ENCODES ONE OF 2 PUTATIVE TYPE-1 PROTEIN PHOSPHATASES [J].

OHKURA, H ;

KINOSHITA, N ;

MIYATANI, S ;

TODA, T ;

YANAGIDA, M .

CELL, 1989, 57 (06) :997-1007

[30] ASSIGNMENT OF THE HUMAN LOCUS DETERMINING PHOSPHOGLYCOLATE PHOSPHATASE (PGP) TO CHROMOSOME-16 [J].

POVEY, S ;

JEREMIAH, SJ ;

BARKER, RF ;

HOPKINSON, DA ;

ROBSON, EB ;

COOK, PJL ;

SOLOMON, E ;

BOBROW, M ;

CARRITT, B ;

BUCKTON, KE .

ANNALS OF HUMAN GENETICS, 1980, 43 (JAN) :241-248

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