EXPRESSION OF VIMENTIN AND EPIDERMAL GROWTH-FACTOR RECEPTOR IN EFFUSIONS FROM PATIENTS WITH BREAST-CANCER - CORRELATION WITH ESTROGEN AND PROGESTERONE-RECEPTOR STATUS

被引：8

作者：

ATHANASSIADOU, P ^{[1
]}

ATHANASSIADES, P ^{[1
]}

KYRKOU, K ^{[1
]}

GIAHNAKI, E ^{[1
]}

GIANNIOTI, E ^{[1
]}

NANAS, S ^{[1
]}

机构：

[1] UNIV ATHENS,SCH MED ALEXANDRA HOSP,DEPT CLIN THERAPEUT,GR-11527 ATHENS,GREECE

来源：

CYTOPATHOLOGY | 1993年 / 4卷 / 02期

关键词：

PLEURAL EFFUSION; IMMUNOCYTOCHEMISTRY; BREAST CARCINOMA; EPIDERMAL GROWTH FACTOR RECEPTOR; VIMENTIN; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; SURVIVAL TIME;

D O I：

10.1111/j.1365-2303.1993.tb00520.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The epidermal growth factor receptor (EGFr) status and the vimentin (V) status of malignant cells in pleural fluids from patients with breast cancer were determined using an immunoperoxidase labelling technique. The results were correlated with the oestrogen receptor (ER) and the progesterone receptor (PR) status of the primary tumour and with disease-free survival time of the patient. A negative correlation between EGFr and V status and hormone receptor status was found. The longest mean survival time occurred in patients with negative EGFr and V status and positive hormone receptor (ER and PR) status. The shortest mean survival time occurred in patients with positive EGFr and V and negative ER and PR status.

引用

页码：91 / 98

页数：8

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