CONVENIENT CHEMICAL RESOLUTION OF A BICYCLIC HYDROXYLACTONE OF SYNTHETIC INTEREST

被引：18

作者：

BURLINA, F ^{[1
]}

CLIVIO, P ^{[1
]}

FOURREY, JL ^{[1
]}

RICHE, C ^{[1
]}

THOMAS, M ^{[1
]}

机构：

[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 44期

关键词：

CHEMICAL RESOLUTION; CONFIGURATION; CYCLOPENTENE; LACTONE SYNTHON;

D O I：

10.1016/0040-4039(94)88268-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The readily available bicyclic lactone 1 was resolved by treatment with (S)-O-acetyllactyl chloride to give a separable pair of diastereoisomers (-)-3 and (-)-4 the respective configuration of which was deduced from X-ray crystallography performed on the bromo derivative (-)-5.

引用

页码：8151 / 8152

页数：2

共 6 条

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[6] SYNTHESIS OF NUCLEOSIDES AND RELATED-COMPOUNDS .33. SYNTHESIS OF 9-(C-5-HYDROXY-C-4-HYDROXYMETHYLCYCLOPENT-2-EN-R-1-YL)-9H-ADENINE [(+/-)-EPINOR-BCA]
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