EFFECT OF OUT-OF-HOSPITAL DEFIBRILLATION BY BASIC LIFE-SUPPORT PROVIDERS ON CARDIAC-ARREST MORTALITY - A METAANALYSIS

被引:96
作者
AUBLE, TE
MENEGAZZI, JJ
PARIS, PM
机构
关键词
D O I
10.1016/S0196-0644(95)70178-8
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Study objective: Although some studies demonstrate otherwise, we hypothesized that metaanalysis would demonstrate a reduction in the relative risk of mortality when basic life support (BLS) providers can defibrillate out-of-hospital cardiac arrest patients. Design: Metaanalysis of studies meeting the following criteria: single-tier or two-tier emergency medical service (EMS) system, survival to hospital discharge for patients in ventricular fibrillation, and manual and/or automatic external defibrillators. The a error rate was .05. Results: Seven trials qualified for metaanalysis. Across all trials, the risk of mortality for BLS care with defibrillation versus that without was .915 (P=.0003). Separate subset analyses of single-tier and two-tier EMS systems demonstrated similar results. Conclusion: BLS defibrillation can reduce the relative risk of death for out-of-hospital cardiac arrest victims in ventricular fibrillation. Weaknesses in individual study designs and regional clustering limit the strength of this metaanalysis and conclusion.
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页码:642 / 648
页数:7
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