PROCESSING AND SURFACE PRESENTATION OF THE MYCOPLASMA-HYORHINIS VARIANT LIPOPROTEIN VLPC

被引：17

作者：

CLEAVINGER, CM ^{[1
]}

KIM, MF ^{[1
]}

WISE, KS ^{[1
]}

机构：

[1] UNIV MISSOURI,DEPT MOLEC MICROBIOL & IMMUNOL,COLUMBIA,MO 65212

来源：

JOURNAL OF BACTERIOLOGY | 1994年 / 176卷 / 08期

关键词：

D O I：

10.1128/JB.176.8.2463-2467.1994

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The variant surface lipoprotein VlpC of Mycoplasma hyorhinis was shown to be processed by cleavage of a characteristic prokaryotic prolipoprotein signal peptide. In addition, a vlpC::phoA fusion protein expressed and translocated in Escherichia coli was recognized by surface-binding monoclonal antibodies, which identified the characteristic region II of Vlps, containing divergent external sequences proximal to the membrane, as an exposed portion of these surface proteins subject to immune recognition and selection.

引用

页码：2463 / 2467

页数：5

共 25 条

[11] TRITON X-114 PHASE FRACTIONATION OF AN INTEGRAL MEMBRANE-SURFACE PROTEIN MEDIATING MONOCLONAL-ANTIBODY KILLING OF MYCOPLASMA-HYORHINIS [J].

RIETHMAN, HC ;

BOYER, MJ ;

WISE, KS .

INFECTION AND IMMUNITY, 1987, 55 (05) :1094-1100

[12] PHENOTYPIC SWITCHING IN MYCOPLASMAS - PHASE VARIATION OF DIVERSE SURFACE LIPOPROTEINS [J].

ROSENGARTEN, R ;

WISE, KS .

SCIENCE, 1990, 247 (4940) :315-318

[13] THE VLP SYSTEM OF MYCOPLASMA-HYORHINIS - COMBINATORIAL EXPRESSION OF DISTINCT SIZE VARIANT LIPOPROTEINS GENERATING HIGH-FREQUENCY SURFACE ANTIGENIC VARIATION [J].

ROSENGARTEN, R ;

WISE, KS .

JOURNAL OF BACTERIOLOGY, 1991, 173 (15) :4782-4793

[14] ANTIGENIC VARIATION IN MYCOPLASMA-HYORHINIS - INCREASED REPERTOIRE OF VARIABLE LIPOPROTEINS EXPANDING SURFACE DIVERSITY AND STRUCTURAL COMPLEXITY [J].

ROSENGARTEN, R ;

THEISS, PM ;

YOGEV, D ;

WISE, KS .

INFECTION AND IMMUNITY, 1993, 61 (05) :2224-2228

[15] PATHOGENICITY OF SWINE MYCOPLASMAS [J].

ROSS, RF .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1973, 225 (DEC14) :347-368

[16] THE 34-KILODALTON MEMBRANE IMMUNOGEN OF TREPONEMA-PALLIDUM IS A LIPOPROTEIN [J].

SWANCUTT, MA ;

RADOLF, JD ;

NORGARD, MV .

INFECTION AND IMMUNITY, 1990, 58 (02) :384-392

[17] A BACTERIOPHAGE-T7 RNA-POLYMERASE PROMOTER SYSTEM FOR CONTROLLED EXCLUSIVE EXPRESSION OF SPECIFIC GENES [J].

TABOR, S ;

RICHARDSON, CC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (04) :1074-1078

[18] MOLECULAR-CLONING, EXPRESSION, AND DNA-SEQUENCE ANALYSIS OF THE GENE THAT ENCODES THE 16-KILODALTON OUTER-MEMBRANE LIPOPROTEIN OF SERPULINA-HYODYSENTERIAE [J].

THOMAS, W ;

SELLWOOD, R .

INFECTION AND IMMUNITY, 1993, 61 (03) :1136-1140

[19]

Wieslander Ake, 1992, P93

[20]

Wise Kim S., 1992, P473

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