NOVEL RECEPTOR ANTAGONISTS WELCOME A NEW ERA IN ENDOTHELIN BIOLOGY

被引：81

作者：

DOUGLAS, SA ^{[1
]}

MEEK, TD ^{[1
]}

OHLSTEIN, EH ^{[1
]}

机构：

[1] BRISTOL MYERS SQUIBB PHARMACEUT RES INST,DEPT CARDIOVASC BIOCHEM,PRINCETON,NJ 08543

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 1994年 / 15卷 / 09期

关键词：

D O I：

10.1016/0165-6147(94)90019-1

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：313 / 316

页数：4

共 12 条

[1] CLONING AND EXPRESSION OF A CDNA-ENCODING AN ENDOTHELIN RECEPTOR [J].

ARAI, H ;

HORI, S ;

ARAMORI, I ;

OHKUBO, H ;

NAKANISHI, S .

NATURE, 1990, 348 (6303) :730-732

[2]

CLOZEL M, IN PRESS J PHARM EXP

[3] 1,3-DIARYLINDAN-2-CARBOXYLIC ACIDS, POTENT AND SELECTIVE NONPEPTIDE ENDOTHELIN RECEPTOR ANTAGONISTS [J].

ELLIOTT, JD ;

LAGO, MA ;

COUSINS, RD ;

GAO, AM ;

LEBER, JD ;

ERHARD, KF ;

NAMBI, P ;

ELSHOURBAGY, NA ;

KUMAR, C ;

LEE, JA ;

BEAN, JW ;

DEBROSSE, CW ;

EGGLESTON, DS ;

BROOKS, DP ;

FEUERSTEIN, G ;

RUFFOLO, RR ;

WEINSTOCK, J ;

GLEASON, JG ;

PEISHOFF, CE ;

OHLSTEIN, EH .

JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (11) :1553-1557

[4] CLEARANCE OF CIRCULATING ENDOTHELIN-1 BY ET(B) RECEPTORS IN RATS [J].

FUKURODA, T ;

FUJIKAWA, T ;

OZAKI, S ;

ISHIKAWA, K ;

YANO, M ;

NISHIKIBE, M .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1994, 199 (03) :1461-1465

[5] BIOCHEMICAL AND PHARMACOLOGICAL PROFILE OF A POTENT AND SELECTIVE ENDOTHELIN B-RECEPTOR ANTAGONIST, BQ-788 [J].

ISHIKAWA, K ;

IHARA, M ;

NOGUCHI, K ;

MASE, T ;

MINO, N ;

SAEKI, T ;

FUKURODA, T ;

FUKAMI, T ;

OZAKI, S ;

NAGASE, T ;

NISHIKIBE, M ;

YANO, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (11) :4892-4896

[6]

KRYSTEK SR, 1994, J BIOL CHEM, V269, P12383

[7]

LEE JA, IN PRESS P NATL ACAD

[8] CLONING OF A CDNA-ENCODING A NON-ISOPEPTIDE-SELECTIVE SUBTYPE OF THE ENDOTHELIN RECEPTOR [J].

SAKURAI, T ;

YANAGISAWA, M ;

TAKUWA, Y ;

MIYAZAKI, H ;

KIMURA, S ;

GOTO, K ;

MASAKI, T .

NATURE, 1990, 348 (6303) :732-735

[9] THE DISCOVERY OF SULFONAMIDE ENDOTHELIN ANTAGONISTS AND THE DEVELOPMENT OF THE ORALLY-ACTIVE ET(A) ANTAGONIST 5-(DIMETHYLAMINO)-N-(3,4-DIMETHYL-5-ISOXAZOLYL)-1-NAPHTHALENESULFONAMIDE [J].

STEIN, PD ;

HUNT, JT ;

FLOYD, DM ;

MORELAND, S ;

DICKINSON, KEJ ;

MITCHELL, C ;

LIU, ECK ;

WEBB, ML ;

MURUGESAN, N ;

DICKEY, J ;

MCMULLEN, D ;

ZHANG, RG ;

LEE, VG ;

SERAFINO, R ;

DELANEY, C ;

SCHAEFFER, TR ;

KOZLOWSKI, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (03) :329-331

[10] COMPARATIVE-STUDIES WITH THE ENDOTHELIN RECEPTOR ANTAGONISTS BQ-123 AND PD-142893 INDICATE AT LEAST 3 ENDOTHELIN RECEPTORS [J].

WARNER, TD ;

ALLCOCK, GH ;

MICKLEY, EJ ;

CORDER, R ;

VANE, JR .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1993, 22 :S117-S120

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