INDUCTION OF ADIPOSE CONVERSION IN 3T3-L1 CELLS IS ASSOCIATED WITH AN EARLY PHOSPHORYLATION OF A PROTEIN PARTLY HOMOLOGOUS WITH MOUSE VIMENTIN

被引:7
作者
BRANDES, R [1 ]
ARAD, R [1 ]
GAATHON, A [1 ]
BARTANA, J [1 ]
机构
[1] HEBREW UNIV JERUSALEM,HADASSAH MED SCH,BLETTERMAN RES LAB MACROMOLEC,IL-91010 JERUSALEM,ISRAEL
关键词
ADIPOCYTE DIFFERENTIATION; 3T3-L1; BEZAFIBRATE; PROTEIN PHOSPHORYLATION; VIMENTIN;
D O I
10.1016/0014-5793(93)80400-O
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Induction of adipose conversion in 3T3-L1 by bezafibrate has been previously shown to be enhanced by dibutyryl cAMP and to be associated with an early phosphorylation of a 60 kDa acidic protein [Biochim. Biophys. Acta 1054 (1990) 219-224; FEBS Lett. 285 (1991) 63-65]. We describe here the isolation and sequencing of two peptides of the protein concerned. Both appear to be homologous with two respective amino acid sequences of the mouse intermediate filament protein vimentin.
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页码:179 / 182
页数:4
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