LOCALIZATION OF ANGIOTENSIN-IV BINDING-SITES TO MOTOR AND SENSORY NEURONS IN THE SHEEP SPINAL-CORD AND HINDBRAIN

被引：39

作者：

MOELLER, I ^{[1
]}

CHAI, SY ^{[1
]}

OLDFIELD, BJ ^{[1
]}

MCKINLEY, MJ ^{[1
]}

CASLEY, D ^{[1
]}

MENDELSOHN, FAO ^{[1
]}

机构：

[1] UNIV MELBOURNE, HOWARD FLOREY INST EXPTL PHYSIOL & MED, PARKVILLE, VIC 3052, AUSTRALIA

来源：

BRAIN RESEARCH | 1995年 / 701卷 / 1-2期

基金：

英国医学研究理事会;

关键词：

SOMATIC; AUTONOMIC; INTERMEDIOLATERAL CELL COLUMN; DORSAL ROOT GANGLIA; RENIN-ANGIOTENSIN SYSTEM;

D O I：

10.1016/0006-8993(95)01128-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In the sheep spinal cord, a high density of [I-125]angiotensin IV binding sites was localized to the perikaryon and processes of all somatic motor neurons, the autonomic motor neurons in the lateral hems of thoracic and lumbar segments and all dorsal root ganglia, but was low in lamina II of all dorsal horns. At supraspinal levels, [I-125]angiotensin IV binding was abundant in numerous motor associated regions, with weaker binding observed in the sensory regions. This wide distribution pattern suggests an important role for the binding site in the central nervous system.

引用

页码：301 / 306

页数：6

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