PROGRESS TOWARD INCREASING FETAL HEMOGLOBIN PRODUCTION IN MAN - EXPERIENCE WITH 5-AZACYTIDINE AND HYDROXYUREA

被引：13

作者：

DOVER, GJ

CHARACHE, S

NORA, R

BOYER, SH

机构：

[1] JOHNS HOPKINS UNIV, SCH MED, DEPT MED, BALTIMORE, MD 21219 USA

[2] JOHNS HOPKINS UNIV, SCH MED, DEPT LAB MED, BALTIMORE, MD 21219 USA

[3] HOWARD HUGHES MED INST, BIOCHEM HUMAN GENET LAB, BALTIMORE, MD 21209 USA

来源：

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES | 1985年 / 445卷 / JUN期

关键词：

D O I：

10.1111/j.1749-6632.1985.tb17191.x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：218 / 224

页数：7

共 23 条

[1]

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[2]

BENEDICT WF, 1977, CANCER RES, V37, P2202

[3] TREATMENT OF SICKLE-CELL-ANEMIA WITH 5-AZACYTIDINE RESULTS IN INCREASED FETAL HEMOGLOBIN PRODUCTION AND IS ASSOCIATED WITH NONRANDOM HYPOMETHYLATION OF DNA AROUND THE GAMMA-DELTA-BETA-GLOBIN GENE-COMPLEX [J].

CHARACHE, S ;

DOVER, G ;

SMITH, K ;

TALBOT, CC ;

MOYER, M ;

BOYER, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (15) :4842-4846

[4]

CLEGG JB, 1983, LANCET, V1, P536

[5]

DERON ATT, 1984, BLOOD, V63, P201

[6] 5-AZACYTIDINE STIMULATES FETAL HEMOGLOBIN-SYNTHESIS IN ANEMIC BABOONS [J].

DESIMONE, J ;

HELLER, P ;

HALL, L ;

ZWIERS, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (14) :4428-4431

[7] PRODUCTION OF ERYTHROCYTES THAT CONTAIN FETAL HEMOGLOBIN IN ANEMIA - TRANSIENT INVIVO CHANGES [J].

DOVER, GJ ;

BOYER, SH ;

ZINKHAM, WH .

JOURNAL OF CLINICAL INVESTIGATION, 1979, 63 (02) :173-176

[8]

DOVER GJ, 1984, CLIN RES, V32, pA551

[9]

DOVER GJ, 1983, BLOOD, V61, P1242

[10]

DOVER GJ, 1980, J CLIN INVEST, V66, P1772

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