ANALYSIS OF NONLINEARITIES IN THE FLICKER ERG

被引：79

作者：

BURNS, SA

ELSNER, AE

KREITZ, MR

机构：

[1] Eye Research Institute of Retina Foundation, Harvard Medical School, Boston, MA

来源：

OPTOMETRY AND VISION SCIENCE | 1992年 / 69卷 / 02期

关键词：

ELECTRORETINOGRAM; ERG; RETINA; NONLINEAR ANALYSIS; TEMPORAL SENSITIVITY;

D O I：

10.1097/00006324-199202000-00002

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The electroretinogram (ERG) response to steadily flickering fields shows significant nonlinear components. These nonlinear components have been used to investigate the ERG. We find the following. (1) The fundamental retinal response can be recorded at frequencies greater than 100 Hz and the second and higher harmonic responses have measurable response frequencies as high as 200 Hz. Both the fundamental response component and the second harmonic response component have multiple local maxima as a function of frequency. (2) Measurement of the response of the retina to the sum of two sine waves indicates that there is an early low-pass temporal filter in the retina. This early filter has a cutoff frequency between 40 and 50 Hz. (3) The high frequency nonlinearity is not a compressive nonlinearity.

引用

页码：95 / 105

页数：11

共 59 条

[41]

Baker C.L., Hess R., Olsen B.T., Zrenner E., Current source density analysis of linear and non-linear components of the primate electroretinogram, J Physiol (Lond), 407, pp. 155-176, (1988)

[42]

Gur M., Zeevi Y., Frequency domain analysis of the human electroretinogram, J Opt Soc Am, 70, pp. 53-59, (1980)

[43]

Tsuchida Y., Kawasaki K., Fujimura K., Jacobson J.H., Isolation of faster components in the electroretinogram and visually evoked response in man, Am J Ophthalmol, 75, pp. 846-852, (1973)

[44]

Boynton R.M., Stray light and the human electroretinogram, J Opt Soc Am, 43, pp. 442-449, (1953)

[45]

Jones R., King-Smith P.E., Loffing D.H., Gaynier F.L., Stray light contribution to the focal electroretinogram (ERG), Clin Vis Sic, 1, pp. 152-160, (1987)

[46]

Swanson W., Ueno T., Smith V.C., Pokorny J., Temporal modulation sensitivity and pulse-detection thresholds for chromatic and luminance perturbations, J Opt Soc Am, 4 A, pp. 1992-2005, (1987)

[47]

Burns S.A., Eisner A.E., Color matching at high illuminances: The color-match-area effect and photopigment bleaching, J Opt Soc Am, 2 A, pp. 698-704, (1985)

[48]

Burns S.A., Eisner A.E., Lobes L.A., Doft B.H., A psychophysical technique for measuring cone photopigment bleaching, Invest Ophthalmol Vis Sci, 28, pp. 711-717, (1987)

[49]

Abraham F.A., Alpern M., Kirk D.B., Electroretinograms evoked by sinusoidal excitation of human cones, J Physiol (Lond), 363, pp. 135-150, (1985)

[50]

Abraham F.A., Alpern M., Factors influencing threshold of the fundamental electrical response to sinusoidal excitation of human photoreceptors, J Physiol (Lond), 357, pp. 151-172, (1984)

← 1 2 3 4 5 6 →