EVALUATION OF 3 GLUTARALDEHYDE-BASED DISINFECTANTS USED IN ENDOSCOPY

被引:8
作者
JETTE, LP
RINGUETTE, L
ISHAK, M
MILLER, M
SAINTANTOINE, P
机构
[1] HOTEL DIEU ST JEROME,ST JEROME,PQ J7Z 5T3,CANADA
[2] SIR MORTIMER B DAVIS JEWISH HOSP,MONTREAL,PQ H3T 1E2,CANADA
[3] UNIV MONTREAL,NOTRE DAME HOSP,MONTREAL,PQ H2L 4M1,CANADA
关键词
GLUTARALDEHYDE DISINFECTANT; INACTIVATION FACTOR;
D O I
10.1016/0195-6701(95)90264-3
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The European suspension test was applied to compare the in vitro activity of three glutaraldehyde-based disinfectants: a 1:10 dilution of a 10% glutaraldehyde solution containing 0.5% phenylphenol-0.1% amylphenol, a 2% acid glutaraldehyde solution, and a 2% alkaline glutaraldehyde solution. The microbicidal effect of the disinfectants was evaluated by counting surviving cells of three indicator microorganisms (Pseudomonas aeruginosa, Mycobacterium chelonae and phage f2) after exposure times of 5, 10, 20 and 40 min to the agents at 20 degrees C. An inactivation factor (IF) of greater than or equal to 5 log(10) was used as the criterion for effective disinfection. This IF was achieved with every microorganism/disinfectant combination after 5 min exposure except in experiments with phage f2 and the 1% glutaradehyde-based disinfectant. The diminished inactivation noticed with the 1% glutaraldehyde-based disinfectant supports the recommendation to use a disinfectant containing a minimum of 2% glutaraldehyde for high level disinfection.
引用
收藏
页码:295 / 303
页数:9
相关论文
共 39 条
  • [31] RUTALA WA, 1993, INFECT CONT HOSP EP, V14, P713
  • [32] RUTALA WA, 1991, INFECT CONT HOSP EP, V12, P282
  • [33] TRANSMISSION OF INFECTION BY GASTROINTESTINAL ENDOSCOPY AND BRONCHOSCOPY
    SPACH, DH
    SILVERSTEIN, FE
    STAMM, WE
    [J]. ANNALS OF INTERNAL MEDICINE, 1993, 118 (02) : 117 - 128
  • [34] GLUTARALDEHYDE RESISTANT MYCOBACTERIA FROM ENDOSCOPE WASHERS
    VANKLINGEREN, B
    PULLEN, W
    [J]. JOURNAL OF HOSPITAL INFECTION, 1993, 25 (02) : 147 - 149
  • [35] William S., 1984, OFFICIAL METHODS ANA
  • [36] 1983, J HOSP INFECT, V4, P101
  • [37] 1991, MMWR-MORBID MORTAL W, V40, P675
  • [38] 1989, RECUEIL NORMES FRANC
  • [39] 1992, TEST METHODS ANTIMIC