KINETIC-ANALYSIS OF TUBULIN EXCHANGE AT MICROTUBULE ENDS AT LOW VINBLASTINE CONCENTRATIONS

被引：78

作者：

JORDAN, MA

WILSON, L

机构：

[1] Department of Biological Sciences, University of California, Santa Barbara

来源：

BIOCHEMISTRY | 1990年 / 29卷 / 11期

关键词：

D O I：

10.1021/bi00463a016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have investigated the effects of vinblastine at micromolar concentrations and below on the dynamics of tubulin exchange at the ends of microtubule-associated-protein-rich bovine brain microtubules. The predominant behavior of these microtubules at polymer-mass steady state under the conditions examined was tubulin flux i.e. © 1990, American Chemical Society. All rights reserved.

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页码：2730 / 2739

页数：10

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