ETHER ANESTHESIA DIFFERENTIALLY AFFECTS THE CONTENT OF PREPRO-CORTICOTROPIN-RELEASING HORMONE, PREPRONEUROTENSIN NEUROMEDIN-N AND PREPRO-ENKEPHALIN MESSENGER-RNAS IN THE HYPOTHALAMIC PARAVENTRICULAR NUCLEUS OF THE RAT

被引：47

作者：

WATTS, AG ^{[1
]}

机构：

[1] SALK INST BIOL STUDIES,NEURAL SYST LAB,LA JOLLA,CA 92037

来源：

BRAIN RESEARCH | 1991年 / 544卷 / 02期

关键词：

MESSENGER RNA; CORTICOTROPIN-RELEASING HORMONE; NEUROTENSIN; ENKEPHALIN; STRESS; PARAVENTRICULAR NUCLEUS; INSITU HYBRIDIZATION;

D O I：

10.1016/0006-8993(91)90080-F

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The content of the mRNAs that code for prepro-corticotropin releasing hormone (ppCRH), prepro-neurotensin/neuromedin N (ppNT/NMN) and prepro-enkephalin (ppENK) was measured using in situ hybridization histochemistry in the various subdivisions of the hypothalamic paraventricular nucleus (PVH) 4 h after a bout of ether anesthesia. This treatment increased the content of ppENK mRNA only in a selected region of the dorsal medial parvicellular PVH (PVHmpd). PpNT/NMN mRNA was undetectable in the PVH of control animals, but hybridization was observed in the PVHmpd of anesthetized animals. The content of ppCRH mRNA was unchanged 4 h after ether aesthesia.

引用

页码：353 / 357

页数：5

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