Pregnancy and multiple sclerosis

被引：25

作者：

Airas, Laura ^{[1
]}

Kaaja, Risto ^{[2
,3
]}

机构：

[1] Turku Univ Hosp, Dept Neurol, FI-20521 Turku, Finland

[2] Satakunta Cent Hosp, Pori, Finland

[3] Turku Univ, Turku, Finland

来源：

OBSTETRIC MEDICINE | 2012年 / 5卷 / 03期

关键词：

multiple sclerosis; pregnancy; immunosuppression;

D O I：

10.1258/om.2012.110014

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The relapse rate of multiple sclerosis (MS) is typically reduced during late pregnancy but increases in the postpartum period. The reasons for the increased postpartum activity are not entirely clear, but factors such as the abrupt decrease in oestrogen levels immediately after the delivery and the loss of the immunosuppressive state of pregnancy are likely of importance. There is a general view that MS does not affect the course or outcome of pregnancy.

引用

页码：94 / 97

页数：4

共 41 条

[1] Effect of intravenous immunoglobulin treatment on pregnancy and postpartum-related relapses in multiple sclerosis [J].

Achiron, A ;

Kishner, I ;

Dolev, M ;

Stern, Y ;

Dulitzky, M ;

Schiff, E ;

Achiron, R .

JOURNAL OF NEUROLOGY, 2004, 251 (09) :1133-1137

[2] BREAST-FEEDING, POSTPARTUM AND PREPREGNANCY DISEASE ACTIVITY IN MULTIPLE SCLEROSIS [J].

Airas, L. ;

Jalkanen, A. ;

Alanen, A. ;

Pirttila, T. ;

Marttila, R. J. .

NEUROLOGY, 2010, 75 (05) :474-476

[3] Pregnancy and fetal outcomes after interferon-β exposure in multiple sclerosis [J].

Amato, M. P. ;

Portaccio, E. ;

Ghezzi, A. ;

Hakiki, B. ;

Zipoli, V. ;

Martinelli, V. ;

Moiola, L. ;

Patti, F. ;

La Mantia, L. ;

Mancardi, G. L. ;

Solaro, C. ;

Tola, M. R. ;

Pozzilli, C. ;

De Giglio, L. ;

Totaro, R. ;

Lugaresi, A. ;

Di Tommaso, V. ;

Paolicelli, D. ;

Marrosu, M. G. ;

Comi, G. ;

Pellegrini, F. ;

Trojano, M. .

NEUROLOGY, 2010, 75 (20) :1794-1802

[4] ANESTHESIA IN MULTIPLE-SCLEROSIS [J].

BAMFORD, C ;

SIBLEY, W ;

LAGUNA, J .

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 1978, 5 (01) :41-44

[5] The reproductive effects of beta interferon therapy in pregnancy - A longitudinal cohort [J].

Boskovic, R ;

Wide, R ;

Wolpin, J ;

Bauer, DJ ;

Koren, G .

NEUROLOGY, 2005, 65 (06) :807-811

[6] Multiple sclerosis [J].

Compston, Alastair ;

Coles, Alasdair .

LANCET, 2008, 372 (9648) :1502-1517

[7] Rate of pregnancy-related relapse in multiple sclerosis [J].

Confavreux, C ;

Hutchinson, M ;

Hours, MM ;

Cortinovis-Tourniaire, P ;

Moreau, T .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (05) :285-291

[8] Pregnancy, delivery, and birth outcome in women with multiple sclerosis [J].

Dahl, J ;

Myhr, KM ;

Daltveit, AK ;

Hoff, JM ;

Gilhus, NE .

NEUROLOGY, 2005, 65 (12) :1961-1963

[9] Pregnancy in multiple sclerosis patients treated with immunomodulators prior to or during part of the pregnancy:: a descriptive study in the Spanish population [J].

De las Heras, V. ;

De Andres, C. ;

Tellez, N. ;

Tintore, M. .

MULTIPLE SCLEROSIS JOURNAL, 2007, 13 (08) :981-984

[10] The first case of mitoxantrone exposure in early pregnancy [J].

De Santis, M. ;

Straface, G. ;

Cavaliere, A. F. ;

Rosati, P. ;

Batocchi, A. P. ;

Caruso, A. .

NEUROTOXICOLOGY, 2007, 28 (03) :696-697

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