THEORY FOR THE EQUATION OF STATE OF PHOSPHOLIPID MONOLAYERS

被引:25
作者
CANTOR, RS
DILL, KA
机构
[1] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143
[2] UNIV CALIF SAN FRANCISCO,DEPT PHARM,SAN FRANCISCO,CA 94143
关键词
PHOSPHORUS COMPOUNDS - Chemical Reactions - THERMODYNAMICS;
D O I
10.1021/la00069a015
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We present a simple theory for the interactions among the phospholipids in bilayers and monolayers over a wide range of surface densities, temperatures, and chain lengths. This work draws from three recent efforts: (1) lattice-based interphase theory which explicitly treats the chain conformations in three-dimensional interfacial phases of short-chain molecules, (2) a recent 'equation of state' treatment of van der Waals interactions which predicts volume changes, enthalpies, and temperatures of melting of the 'rotator' phases of n-alkanes, and (3) detailed study of the extensive measurements of Mingins et al. of pressure-area isotherms of phosphatidylcholines at the heptane/water interface which we have used to assess empirical characteristics of the head group interactions and of the 'solid state'.
引用
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页码:331 / 337
页数:7
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