A PHENOXY-BRIDGED HOMODINUCLEAR ZN COMPLEX WITH AN UNUSUAL COORDINATION SPHERE - MODEL-COMPOUND FOR THE ACTIVE-SITE OF PHOSPHOLIPASE-C

被引：87

作者：

UHLENBROCK, S ^{[1
]}

KREBS, B ^{[1
]}

机构：

[1] UNIV MUNSTER,INST ANORGAN CHEM,WILHELM KLEMM STR 8,W-4400 MUNSTER,GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1992年 / 31卷 / 12期

关键词：

D O I：

10.1002/anie.199216471

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The imitation of not only the structure but also the function of the active site of the metalloenzyme phospholipase C seems to have been achieved with complex 1 (O(w) = OH2). The two Zn atoms in 1 are bridged by a phenoxy and a carboxylate group. In addition, one Zn atom binds an H2O molecule, which is important for the catalytic process. [Zn2(bbap)H2O(mu-OBz)]2+ 1 Hbbap = bis[bis(benzimidazolylmethyl)aminomethyl]methylphenol

引用

页码：1647 / 1648

页数：2

共 26 条

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