A NEW SYNTHETIC ROUTE TO MACROCYCLES - SYNTHESIS OF LARGE RING ENAMINOLACTONES

被引：10

作者：

JOURDAIN, F ^{[1
]}

POMMELET, JC ^{[1
]}

机构：

[1] UNIV CAEN,ISMRA,CNRS,COMPOSES THIOORGAN LAB,F-14050 CAEN,FRANCE

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(00)76754-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Macrocyclic enaminolactones 5 are prepared in three steps from commercialy available chloroalcohols 1. The cyclization step is performed by intramolecular nucleophilic addition of the hydroxy group to an aminomethyleneketene generated by thermolysis.

引用

页码：1545 / 1548

页数：4

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