PREVALENCE OF HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE-1 (HTLV-1) AND HTLV-2 INFECTION AMONG SPANISH DRUG-USERS MEASURED BY HTLV-1 ASSAY AND HTLV-1 AND HTLV-2 ASSAY

被引：24

作者：

HENRARD, DR

SORIANO, V

ROBERTSON, E

GUTIERREZ, M

STEPHENS, J

DRONDA, F

MILES, F

PUJOL, E

BUYTENDORP, M

CASTRO, A

CHAN, E

VALLEJO, A

LLIBRE, J

MOTLEY, C

PRILLAMAN, J

CALDERON, E

LEAL, M

TUSET, C

MARTINEZZAPICO, R

CABALLERO, E

ORTIZ, R

EIROS, J

AGUILERA, A

ULLOA, F

MARTIN, AM

RODRIGUEZIGLESIAS, A

RIVERA, A

BOUZA, E

ESPARZA, B

MERINO, F

TOR, J

ESCUDERO, D

RIBERA, J

DELROMERO, J

RODRIGUEZ, C

PEDREIRA, J

HEREDIA, A

HEWLETT, I

GONZALEZLAHOZ, J

机构：

[1] ABBOTT LABS,RETROVIRUS RES & DEV,ABBOTT PK,IL 60064

[2] INST SALUD CARLOS 3,MADRID,SPAIN

[3] HOSP PENITENCIARO,MADRID,SPAIN

[4] HOSP JUAN RAMON JIMENEZ,HUELVA,SPAIN

[5] HOSP JUAN CANALEJO,LA CORUNA,SPAIN

[6] HOSP ST JAUME,CALELLA,SPAIN

[7] US FDA,CTR BIOL,RETROVIRUS LAB,BETHESDA,MD 20014

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1995年 / 33卷 / 07期

关键词：

D O I：

10.1128/JCM.33.7.1735-1738.1995

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The prevalence of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 infection in 1992 and 1993 was determined by testing 2,152 specimens from injection drug users living in 11 geographic areas of Spain. Results obtained by an authentic HTLV-1 and -2 test were compared with those obtained by an HTLV-1 assay. HTLV infection was identified in 7 of 11 regions, with an overall prevalence of 2.5% (range, 0.4 to 11.5%). Fourty-four (81%) of 54 subjects were infected with HTLV-2; the viral strains in the remaining 10 subjects could not be serologically typed. Underestimation of HTLV infection because of the low sensitivities of HTLV-1 enzyme immunoassays for HTLV-2 antibody was relatively low (<20%). Therefore, previous epidemiologic findings generated with HTLV-1 enzyme immunoassays appear to be reasonably accurate. Our results suggest that the rate of HTLV infection may have been increasing recently among Spanish drug users.

引用

页码：1735 / 1738

页数：4

共 18 条

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