HISTONE-H1 AND THE REGULATION OF TRANSCRIPTION OF EUKARYOTIC GENES

被引：123

作者：

ZLATANOVA, J

机构：

[1] Molecular Genetics Laboratory, Institute of Genetics, Bulgarian Academy of Sciences

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 07期

关键词：

D O I：

10.1016/0968-0004(90)90053-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Histone H1 plays a role in the formation of chromatin structure, both at the level of the nucleosome particle itself and in the formation of the higher-order structures of the chromatin fibre. Histone H1 is regarded as a part of a general repressor mechanism that ensures a strong and stable repression of gene expression. In addition to serving as a general repressor for relatively large chromatin fragments, histone H1 might also be involved in controlling the transcriptional activity of individual genes. © 1990.

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页码：273 / 276

页数：4

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