FORMATION OF A NITRO DERIVATIVE OF 2-AMINO-3,4-DIMETHYLIMIDAZO[4,5-F]QUINOLINE BY PHOTOIRRADIATION

被引：13

作者：

HIROSE, M

WAKABAYASHI, K

GRIVAS, S

DEFLORA, S

ARAKAWA, N

NAGAO, M

SUGIMURA, T

机构：

[1] UNIV GENOA,INST HYG & PREVENT MED,I-16132 GENOA,ITALY

[2] OCHANOMIZU UNIV,DEPT FOOD & NUTR,BUNKYO KU,TOKYO 112,JAPAN

来源：

CARCINOGENESIS | 1990年 / 11卷 / 05期

关键词：

D O I：

10.1093/carcin/11.5.869

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A direct-acting mutagen to Salmonella typhimurium TA98 was found to be formed by exposing 2-amino-3,4-dlmethylimidazo- [4,5-f]quinoline (MeIQ) in acetone to sunlight for 60 min. The direct-acting mutagen in the irradiated sample was purified by HPLC and identified as 3,4-dimethyl-2-nitrolmidazo- [4,5-f]quinoline (NO2-MeIQ). The yield of NO2-MeIQ from MeIQ was estimated to be 0.3%. © 1990 Oxford University Press.

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页码：869 / 871

页数：3

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