CONVERSION OF ENVIRONMENTAL-POLLUTANT TO MUTAGENS BY VISIBLE-LIGHT

被引:27
作者
MCCOY, EC
HYMAN, J
ROSENKRANZ, HS
机构
[1] Department of Microbiology New York Medical College Valhalla
关键词
D O I
10.1016/0006-291X(79)90690-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Illumination of DMBA [7,12-dimethylbenz(a)anthracene] 3-methlcholanthrene, 2-aminoanthracene and chrysene with visible light resulted in the formation of direct-acting chemicals endowed with genotoxic and frameshift mutagenic activities [as shown by experiments with Salmonella typhimurium TA98 strain]. These findings may be of relevance in assessing the potential [human] health hazards inherent in the planned conversion to disel fuels which is expected to result in increased atmospheric levels of polycyclic aromatic hydrocarbons.
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页码:729 / 734
页数:6
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