CONVERSION OF ENVIRONMENTAL-POLLUTANT TO MUTAGENS BY VISIBLE-LIGHT

被引：27

作者：

MCCOY, EC

HYMAN, J

ROSENKRANZ, HS

机构：

[1] Department of Microbiology New York Medical College Valhalla

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 89卷 / 02期

关键词：

D O I：

10.1016/0006-291X(79)90690-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Illumination of DMBA [7,12-dimethylbenz(a)anthracene] 3-methlcholanthrene, 2-aminoanthracene and chrysene with visible light resulted in the formation of direct-acting chemicals endowed with genotoxic and frameshift mutagenic activities [as shown by experiments with Salmonella typhimurium TA98 strain]. These findings may be of relevance in assessing the potential [human] health hazards inherent in the planned conversion to disel fuels which is expected to result in increased atmospheric levels of polycyclic aromatic hydrocarbons.

引用

页码：729 / 734

页数：6

共 23 条

[11] Knowles A, 1972, Res Prog Org Biol Med Chem, V3 Pt 1, P183
[12] EFFECT OF SODIUM AZIDE ON PHOTODYNAMIC INDUCTION OF GENETIC CHANGES IN YEAST
KOBAYASHI, K
[J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1978, 28 (4-5) : 535 - 538
[13] EFFECTS OF SPECTRAL DIFFERENCES IN ILLUMINATION ON FATIGUE
MAAS, JB
JAYSON, JK
KLEIBER, DA
[J]. JOURNAL OF APPLIED PSYCHOLOGY, 1974, 59 (04) : 524 - 526
[14] HIGH MICROSOME-MEDIATED MUTAGENICITY OF 3,4-DIHYDRODIOL OF 7-METHYLBENZ[A]ANTHRACENE IN S-TYPHIMURIUM TA98
MALAVEILLE, C
TIERNEY, B
GROVER, PL
SIMS, P
BARTSCH, H
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 75 (02) : 427 - 433
[15] MUTAGENICITY AND DNA-MODIFYING ACTIVITY - COMPARISON OF 2 MICROBIAL ASSAYS
ROSENKRANZ, HS
GUTTER, B
SPECK, WT
[J]. MUTATION RESEARCH, 1976, 41 (01): : 61 - 70
[16] SLATER EE, 1971, CANCER RES, V31, P970
[17] BASE SUBSTITUTION MUTATIONS INDUCED IN SALMONELLA STRAINS BY VISIBLE LIGHT (450 NM)
SPECK, WT
ROSENKRANZ, HS
[J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1975, 21 (05) : 369 - 371
[18] CHARACTERIZATION OF A PHOTOPRODUCT OF 7,12-DIMETHYLBENZ[A]ANTHRACENE AND ITS EFFECTS ON CHICK-EMBRYO CELLS IN CULTURE
WARSHAWSKY, D
KERNS, E
BISSELL, MJ
CALVIN, M
[J]. BIOCHEMICAL JOURNAL, 1977, 164 (03) : 481 - 486
[19] WISLOCKI PG, 1976, CANCER RES, V36, P3350
[20] WOOD AW, 1978, CANCER RES, V38, P1967

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