CYTOMEGALOVIRUS POLYRADICULOPATHY CAUSED BY A GANCICLOVIR-RESISTANT STRAIN

被引：17

作者：

TOKUMOTO, JIN

HOLLANDER, H

机构：

[1] UNIV CALIF SAN FRANCISCO, AIDS CLIN, BOX 0378, SAN FRANCISCO, CA 94143 USA

[2] UNIV CALIF SAN FRANCISCO, DIV INFECT DIS, SAN FRANCISCO, CA 94143 USA

来源：

CLINICAL INFECTIOUS DISEASES | 1993年 / 17卷 / 05期

关键词：

D O I：

10.1093/clinids/17.5.854

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Polyradiculopathy caused by cytomegalovirus (CMV) is a rare but serious neurological disorder that occurs late in the course of HIV-1 infection and is potentially treatable with antimicrobial agents active against CMV. We describe a patient with CMV infection caused by a strain that was resistant to ganciclovir. This case demonstrates one potential mechanism of therapeutic failure and illustrates the potential pathogenicity of strains that are resistant to antiviral drugs.

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页码：854 / 856

页数：3

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