TRIMETHYLORTHOFORMATE - A MILD AND EFFECTIVE DEHYDRATING REAGENT FOR SOLUTION AND SOLID-PHASE IMINE FORMATION

被引：158

作者：

LOOK, GC

MURPHY, MM

CAMPBELL, DA

GALLOP, MA

机构：

[1] Affymax Research Institute, Palo Alto, CA 94304

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 17期

关键词：

D O I：

10.1016/0040-4039(95)00442-F

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Trimethylorthoformate has been found to be an effective dehydrating solvent for the formation of imines, both in the solid phase as well as solution phase.

引用

页码：2937 / 2940

页数：4

共 21 条

[1] NON-DECARBOXYLATIVE 1,3-DIPOLAR CYCLOADDITIONS OF IMINES OF ALPHA-AMINO-ACIDS AS A ROUTE TO PROLINE DERIVATIVES [J].

ALY, MF ;

YOUNES, MI ;

METWALLY, SAM .

TETRAHEDRON, 1994, 50 (10) :3159-3168

[2] FLUORONAPHTHYRIDINES AS ANTIBACTERIAL AGENTS .4. SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF 5-SUBSTITUTED-6-FLUORO-7-(CYCLOALKYLAMINO)-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS [J].

BOUZARD, D ;

DICESARE, P ;

ESSIZ, M ;

JACQUET, JP ;

LEDOUSSAL, B ;

REMUZON, P ;

KESSLER, RE ;

FUNGTOMC, J .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (03) :518-525

[3]

CHANCELLOR T, 1994, SYNTHESIS-STUTTGART, P1023

[4] DIVERSOMERS - AN APPROACH TO NONPEPTIDE, NONOLIGOMERIC CHEMICAL DIVERSITY [J].

DEWITT, SH ;

KIELY, JS ;

STANKOVIC, CJ ;

SCHROEDER, MC ;

CODY, DMR ;

PAVIA, MR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (15) :6909-6913

[5] LANTHANOIDS IN ORGANIC-SYNTHESIS .4. SELECTIVE KETALIZATION AND REDUCTION OF CARBONYL GROUPS [J].

GEMAL, AL ;

LUCHE, JL .

JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (23) :4187-4189

[6]

KUZNETSOV VV, 1991, ZH ORG KHIM+, V27, P1579

[7]

LOOK G, UNPUB

[8] METHODS FOR COMBINATORIAL ORGANIC-SYNTHESIS - THE USE OF FAST C-13 NMR ANALYSIS FOR GEL PHASE REACTION MONITORING [J].

LOOK, GC ;

HOLMES, CP ;

CHINN, JP ;

GALLOP, MA .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (25) :7588-7590

[9] SYNTHESIS OF STERICALLY HINDERED IMINES [J].

LOVE, BE ;

REN, JH .

JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (20) :5556-5557

[10]

Moffett RB, 1963, ORG SYNTH, V4, P605

← 1 2 3 →