CALPAINS IN LENS EPITHELIUM FROM PATIENTS WITH CATARACT

被引：26

作者：

ANDERSSON, M ^{[1
]}

SJOSTRAND, J ^{[1
]}

ANDERSSON, AK ^{[1
]}

ANDERSEN, B ^{[1
]}

KARLSSON, JO ^{[1
]}

机构：

[1] GOTHENBURG UNIV,DEPT OPHTHALMOL,GOTHENBURG,SWEDEN

来源：

EXPERIMENTAL EYE RESEARCH | 1994年 / 59卷 / 03期

关键词：

CALPAINS; PROTEASE; LENS EPITHELIUM; HUMAN LENS; CATARACT;

D O I：

10.1006/exer.1994.1118

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Lens epithelium from patients with cataract was obtained during surgery and frozen. The samples were subjected to SDS-electrophoresis and Western blotting. Calpains were quantified using polyclonal antibodies against m- and mu-calpain. m-Calpain could be detected but not the isoenzyme mu-calpain, indicating that m-calpain is the significant most important calpain in human lens epithelium. Quantification of m-calpain showed no relationship to age or gender, but there were significant differences between different types of cataract.

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收藏

页码：359 / 364

页数：6

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