AZOLE RESISTANCE IN OROPHARYNGEAL CANDIDA-ALBICANS STRAINS ISOLATED FROM PATIENTS INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS

被引：49

作者：

HE, XG ^{[1
]}

TIBALLI, RN ^{[1
]}

ZARINS, LT ^{[1
]}

BRADLEY, SF ^{[1
]}

SANGEORZAN, JA ^{[1
]}

KAUFFMAN, CA ^{[1
]}

机构：

[1] UNIV MICHIGAN,DEPT VET AFFAIRS MED CTR,SCH MED,DEPT INTERNAL MED,DIV INFECT DIS,ANN ARBOR,MI 48105

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 10期

关键词：

D O I：

10.1128/AAC.38.10.2495

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

For 212 oropharyngeal isolates of Candida albicans, the fluconazole MICs for 50 and 90% of strains tested were 0.5 and 16 mu g/ml, respectively, and those of itraconazole were 0.05 and 0.2 mu g/ml, respectively. Of 16 isolates for which fluconazole MICs were >64 mu g/ml, itraconazole MICs for 14 were less than or equal to 0.8 mu g/ml and for 2 were >6.4 mu g/ml. Most fluconazole-resistant strains remained susceptible to itraconazole;,whether itraconazole will prove effective for refractory thrush remains to be shown.

引用

页码：2495 / 2497

页数：3