CHANGING PATTERNS OF GLUCOSE-METABOLISM DURING THE COURSE OF SUBACUTE SCLEROSING PANENCEPHALITIS AS MEASURED WITH 18FDG-POSITRON-EMISSION TOMOGRAPHY

被引：9

作者：

HUBER, M

PAWLIK, G

BAMBORSCHKE, S

FINK, GR

KARBE, H

SCHLENKER, M

BEWERMEYER, H

HEISS, WD

机构：

[1] MAX PLANCK INST NEUROL RES,GLEUELERSTR 50,W-5000 COLOGNE 41,GERMANY

[2] UNIV COLOGNE,NEUROL KLIN,W-5000 COLOGNE 41,GERMANY

[3] STADT KRANKENHAUS,W-5090 LEVERKUSEN,GERMANY

来源：

JOURNAL OF NEUROLOGY | 1992年 / 239卷 / 03期

关键词：

18FDG-POSITRON EMISSION TOMOGRAPHY; SUBACUTE SCLEROSING PANENCEPHALITIS; GLUCOSE METABOLISM;

D O I：

10.1007/BF00833917

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

(FDG)-F-18-positron emission tomography performed at different stages in the course of subacute sclerosing panencephalitis revealed a changing pattern of metabolic disturbance. In clinical stage II patients the inflammation in the basal ganglia appeared to lead to neuronal excitation accompanied by hypermetabolism. Widespread cortical functional inhibition of metabolism followed. The striatal inflammation ended with necrosis and hypometabolism, with resulting functional cortical disinhibition; later, deep midbrain structures and brain stem became hypermetabolic. A patient clinically in remission showed no such changes in cerebral glucose metabolism.

引用

收藏

页码：157 / 161

页数：5

相关论文

共 14 条

[1] SIGNS OF FOCAL POSTERIOR CEREBRAL ABNORMALITY IN EARLY SUBACUTE SCLEROSING PANENCEPHALITIS [J].

BEGEER, JH ;

HAAXMA, R ;

SNOEK, JW ;

BOONSTRA, S ;

LECOULTRE, R .

ANNALS OF NEUROLOGY, 1986, 19 (02) :200-202

[2] DETECTION AND IDENTIFICATION OF VIRUS-SPECIFIC, OLIGOCLONAL IGG IN UNCONCENTRATED CEREBROSPINAL-FLUID BY IMMUNOBLOT TECHNIQUE [J].

DORRIES, R ;

TERMEULEN, V .

JOURNAL OF NEUROIMMUNOLOGY, 1984, 7 (2-3) :77-89

[3] SUBACUTE SCLEROSING PANENCEPHALITIS - CURRENT STATUS [J].

DYKEN, PR .

NEUROLOGIC CLINICS, 1985, 3 (01) :179-196

[4] CEREBROSPINAL-FLUID VIRUS-ANTIBODIES - A DIAGNOSTIC INDICATOR FOR MULTIPLE-SCLEROSIS [J].

FELGENHAUER, K ;

SCHADLICH, HJ ;

NEKIC, M ;

ACKERMANN, R .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 1985, 71 (2-3) :291-299

[5] REGIONAL KINETIC CONSTANTS AND CEREBRAL METABOLIC-RATE FOR GLUCOSE IN NORMAL HUMAN VOLUNTEERS DETERMINED BY DYNAMIC POSITRON EMISSION TOMOGRAPHY OF [F-18]-2-FLUORO-2-DEOXY-D-GLUCOSE [J].

HEISS, WD ;

PAWLIK, G ;

HERHOLZ, K ;

WAGNER, R ;

GOLDNER, H ;

WIENHARD, K .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1984, 4 (02) :212-223

[6] COMPUTER-ASSISTED MAPPING IN QUANTITATIVE-ANALYSIS OF CEREBRAL POSITRON EMISSION TOMOGRAMS [J].

HERHOLZ, K ;

PAWLIK, G ;

WIENHARD, K ;

HEISS, WD .

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1985, 9 (01) :154-161

[7] CEREBRAL GLUCOSE-METABOLISM IN THE COURSE OF SUBACUTE SCLEROSING PANENCEPHALITIS [J].

HUBER, M ;

HERHOLZ, K ;

PAWLIK, G ;

SZELIES, B ;

JURGENS, R ;

HEISS, WD .

ARCHIVES OF NEUROLOGY, 1989, 46 (01) :97-100

[8]

JABBOUR JT, 1969, J AMER MED ASSOC, V207, P2248

[9] SUBACUTE SCLEROSING PANENCEPHALITIS - CORRELATION OF CLINICAL, NEUROPHYSIOLOGIC AND NEUROPATHOLOGIC FINDINGS [J].

OHYA, T ;

MARTINEZ, AJ ;

JABBOUR, JT ;

LEMMI, H ;

DUENAS, DA .

NEUROLOGY, 1974, 24 (03) :211-218

[10] STATISTICAL-ANALYSIS OF FUNCTIONAL NEUROIMAGING DATA - EXPLORATORY VERSUS INFERENTIAL METHODS [J].

PAWLIK, G .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1991, 11 (02) :A136-A139