CHANGING PATTERNS OF GLUCOSE-METABOLISM DURING THE COURSE OF SUBACUTE SCLEROSING PANENCEPHALITIS AS MEASURED WITH 18FDG-POSITRON-EMISSION TOMOGRAPHY

被引：9

作者：

HUBER, M

PAWLIK, G

BAMBORSCHKE, S

FINK, GR

KARBE, H

SCHLENKER, M

BEWERMEYER, H

HEISS, WD

机构：

[1] MAX PLANCK INST NEUROL RES,GLEUELERSTR 50,W-5000 COLOGNE 41,GERMANY

[2] UNIV COLOGNE,NEUROL KLIN,W-5000 COLOGNE 41,GERMANY

[3] STADT KRANKENHAUS,W-5090 LEVERKUSEN,GERMANY

来源：

JOURNAL OF NEUROLOGY | 1992年 / 239卷 / 03期

关键词：

18FDG-POSITRON EMISSION TOMOGRAPHY; SUBACUTE SCLEROSING PANENCEPHALITIS; GLUCOSE METABOLISM;

D O I：

10.1007/BF00833917

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

(FDG)-F-18-positron emission tomography performed at different stages in the course of subacute sclerosing panencephalitis revealed a changing pattern of metabolic disturbance. In clinical stage II patients the inflammation in the basal ganglia appeared to lead to neuronal excitation accompanied by hypermetabolism. Widespread cortical functional inhibition of metabolism followed. The striatal inflammation ended with necrosis and hypometabolism, with resulting functional cortical disinhibition; later, deep midbrain structures and brain stem became hypermetabolic. A patient clinically in remission showed no such changes in cerebral glucose metabolism.

引用

页码：157 / 161

页数：5