Urinary Markers of Glomerular Injury in Diabetic Nephropathy

被引：49

作者：

Cohen-Bucay, Abraham ^{[1
]}

Viswanathan, Gautham ^{[2
]}

机构：

[1] Tufts Univ, St Elizabeths Med Ctr, Sch Med, Dept Med, Boston, MA 02135 USA

[2] Tufts Med Ctr, Div Nephrol, Boston, MA 02111 USA

来源：

INTERNATIONAL JOURNAL OF NEPHROLOGY | 2012年 / 2012卷

关键词：

D O I：

10.1155/2012/146987

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Diabetic nephropathy, the leading cause of renal failure worldwide, affects approximately one-third of all people with diabetes. Microalbuminuria is considered the first sign and the best predictor of progression to renal failure and cardiovascular events. However, albuminuria has several limitations. Therefore, earlier, more sensitive and specific biomarkers with greater predictability are needed. The aim of this paper is to discuss the current literature on biomarkers of glomerular injury that have been implicated in diabetic kidney disease.

引用

页数：11

共 140 条

[1] Development and progression of nephropathy in type 2 diabetes: The United Kingdom Prospective Diabetes Study (UKPDS 64) [J].

Adler, AI ;

Stevens, RJ ;

Manley, SE ;

Bilous, RW ;

Cull, CA ;

Holman, RR .

KIDNEY INTERNATIONAL, 2003, 63 (01) :225-232

[2]

American Diabetes Association, 2011, Diabetes Care, V34 Suppl 1, pS4, DOI 10.2337/dc11-S004

[3] The Clinical Characteristics of Normoalbuminuric Renal Insufficiency in Korean Type 2 Diabetic Patients: A Possible Early Stage Renal Complication [J].

An, Jee Hyun ;

Cho, Young Min ;

Yu, Hyeong Gon ;

Jang, Hak Chul ;

Park, Kyong Soo ;

Kim, Seong Yeon ;

Lee, Hong Kye .

JOURNAL OF KOREAN MEDICAL SCIENCE, 2009, 24 :S75-S81

[4]

Andersen S, 2000, KIDNEY INT, V58, P2129

[5] PATHOGENESIS OF DIABETIC GLOMERULOPATHY - HEMODYNAMIC CONSIDERATIONS [J].

ANDERSON, S ;

BRENNER, BM .

DIABETES-METABOLISM REVIEWS, 1988, 4 (02) :163-177

[6] Urine IgM excretion predicts outcome in ANCA-associated renal vasculitis [J].

Bakoush, O ;

Segelmark, M ;

Torffvit, O ;

Ohlsson, S ;

Tencer, J .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2006, 21 (05) :1263-1269

[7]

Bakoush O, 2003, CLIN NEPHROL, V59, P345

[8] Higher urinary IgM excretion in type 2 diabetic nephropathy compared to type 1 diabetic nephropathy [J].

Bakoush, O ;

Tencer, J ;

Tapia, J ;

Rippe, B ;

Torffvit, O .

KIDNEY INTERNATIONAL, 2002, 61 (01) :203-208

[9] High proteinuria selectivity index based upon IgM is a strong predictor of poor renal survival in glomerular diseases [J].

Bakoush, O ;

Torffvit, O ;

Rippe, B ;

Tencer, J .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2001, 16 (07) :1357-1363

[10] GLOMERULAR CHARGE SELECTIVITY AND THE INFLUENCE OF IMPROVED BLOOD-GLUCOSE CONTROL IN TYPE-1 (INSULIN-DEPENDENT) DIABETIC-PATIENTS WITH MICROALBUMINURIA [J].

BANGSTAD, HJ ;

KOFOEDENEVOLDSEN, A ;

DAHLJORGENSEN, K ;

HANSSEN, KF .

DIABETOLOGIA, 1992, 35 (12) :1165-1169

← 1 2 3 4 5 6 7 8 9 10 →