Urinary Markers of Glomerular Injury in Diabetic Nephropathy

被引：49

作者：

Cohen-Bucay, Abraham ^{[1
]}

Viswanathan, Gautham ^{[2
]}

机构：

[1] Tufts Univ, St Elizabeths Med Ctr, Sch Med, Dept Med, Boston, MA 02135 USA

[2] Tufts Med Ctr, Div Nephrol, Boston, MA 02111 USA

来源：

INTERNATIONAL JOURNAL OF NEPHROLOGY | 2012年 / 2012卷

关键词：

D O I：

10.1155/2012/146987

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Diabetic nephropathy, the leading cause of renal failure worldwide, affects approximately one-third of all people with diabetes. Microalbuminuria is considered the first sign and the best predictor of progression to renal failure and cardiovascular events. However, albuminuria has several limitations. Therefore, earlier, more sensitive and specific biomarkers with greater predictability are needed. The aim of this paper is to discuss the current literature on biomarkers of glomerular injury that have been implicated in diabetic kidney disease.

引用

页数：11

共 140 条

[91] Glycemic control reverses increases in urinary excretions of immunoglobulin G and ceruloplasmin in type 2 diabetic patients with normoalbuminuria [J].

Narita, T ;

Fujita, H ;

Koshimura, J ;

Meguro, H ;

Kitazato, H ;

Shimotomai, T ;

Kagaya, E ;

Suzuki, K ;

Murata, M ;

Usami, A ;

Ito, S .

HORMONE AND METABOLIC RESEARCH, 2001, 33 (06) :370-378

[92] Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes [J].

Nieuwdorp, M ;

Mooij, HL ;

Kroon, J ;

Atasever, B ;

Spaan, JAE ;

Ince, C ;

Holleman, F ;

Diamant, M ;

Heine, RJ ;

Hoekstra, JBL ;

Kastelein, JJP ;

Stroes, ESG ;

Vink, H .

DIABETES, 2006, 55 (04) :1127-1132

[93] Albuminuria and Kidney Function Independently Predict Cardiovascular and Renal Outcomes in Diabetes [J].

Ninomiya, Toshiharu ;

Perkovic, Vlado ;

de Galan, Bastiaan E. ;

Zoungas, Sophia ;

Pillai, Avinesh ;

Jardine, Meg ;

Patel, Anushka ;

Cass, Alan ;

Neal, Bruce ;

Poulter, Neil ;

Mogensen, Carl-Erik ;

Cooper, Mark ;

Marre, Michel ;

Williams, Bryan ;

Hamet, Pavel ;

Mancia, Giuseppe ;

Woodward, Mark ;

MacMahon, Stephen ;

Chalmers, John .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2009, 20 (08) :1813-1821

[94]

Nishimura M, 2001, CLIN NEPHROL, V56, P96

[95] TRANSFERRINURIA IN TYPE-2 DIABETES - THE EFFECT OF GLYCEMIC CONTROL [J].

ODONNELL, MJ ;

WATSON, J ;

MARTIN, P ;

CHAPMAN, C ;

BARNETT, AH .

ANNALS OF CLINICAL BIOCHEMISTRY, 1991, 28 :174-177

[96] URINARY TRANSFERRIN EXCRETION IN TYPE-1 (INSULIN-DEPENDENT) DIABETES-MELLITUS [J].

ODONNELL, MJ ;

MARTIN, P ;

FLORKOWSKI, CM ;

TOOP, MJ ;

CHAPMAN, C ;

HOLDER, R ;

BARNETT, AH .

DIABETIC MEDICINE, 1991, 8 (07) :657-661

[97] INCREASED URINARY TRANSFERRIN EXCRETION IN EXERCISING NORMOALBUMINURIC INSULIN-DEPENDENT DIABETIC-PATIENTS [J].

ODONNELL, MJ ;

MARTIN, P ;

CAVAN, D ;

PARKES, A ;

CHAPMAN, J ;

CHAPMAN, C ;

BARNETT, AH .

ANNALS OF CLINICAL BIOCHEMISTRY, 1991, 28 :456-460

[98] Urinary excretions of lipocalin-type prostaglandin D2 synthase predict the development of proteinuria and renal injury in OLETF rats [J].

Ogawa, M ;

Hirawa, N ;

Tsuchida, T ;

Eguchi, N ;

Kawabata, Y ;

Numabe, A ;

Negoro, H ;

Hakamada-Taguchi, R ;

Seiki, K ;

Umemura, S ;

Urade, Y ;

Uehara, Y .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2006, 21 (04) :924-934

[99]

Okonogi H, 2001, CLIN NEPHROL, V55, P357

[100]

OLGEMOLLER B, 1993, CLIN INVESTIGATOR, V71, pS13

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