IRREVERSIBLE ENZYME INHIBITORS 99 - INHIBITORS OF THYMIDINE PHOSPHORYLASE .7. FURTHER STUDIES ON HYDROPHOBIC BONDING WITH HYDROCARBON SUBSTITUENTS ON ACIDIC URACILS

被引：13

作者：

BAKER, BR

KAWAZU, M

MCCLURE, JD

机构：

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1967年 / 56卷 / 09期

关键词：

D O I：

10.1002/jps.2600560906

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

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页码：1081 / &

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[1] IRREVERSIBLE ENZYME INHIBITORS .75. INHIBITORS OF THYMIDINE PHOSPHORTLASE .I. MODE OF RIBOFURANOSE BINDING [J].

BAKER, BR .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :297-&

[2] FACTORS IN DESIGN OF ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS [J].

BAKER, BR .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1964, 53 (04) :347-&

[3] ANALOGS OF TETRAHYDROFOLIC ACID .26. SYNTHESIS OF SOME 5-ARYL AND 5-ARALKYL PYRIMIDINE-6-CARBOXYLIC ACIDS AND THEIR EFFECT ON DIHYDROFOLIC REDUCTASE AND THYMIDYLATE SYNTHETASE [J].

BAKER, BR ;

JORDAAN, JH .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1965, 2 (02) :162-&

[4] IRREVERSIBLE ENZYME INHIBITORS .77. INHIBITORS OF THYMIDINE PHOSPHORYLASE .3. HYDROPHOBIC BONDING BY 1-SUBSTITUTED URACILS CONTAINING ADDITIONAL SUBSTITUENTS AT 5 AND 6 POSITIONS [J].

BAKER, BR ;

KAWAZU, M ;

SANTI, DV ;

SCHWAN, TJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :304-&

[5] IRREVERSIBLE ENZYME INHIBITORS .85| ON MODE OF PYRIMIDINE BINDING OF 5-ALKYL AND 5-ARYLPYRIMIDINES TO DIHYDROFOLIC REDUCTASE [J].

BAKER, BR ;

LOURENS, GJ ;

JORDAAN, JH .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1967, 4 (01) :39-&

[6] IRREVERSIBLE ENZYME INHIBITORS .80. INHIBITORS OF THYMIDINE PHOSPHORYLASE .6. HYDROPHOBIC BONDING WITH 6 SUBSTITUENTS ON ACIDIC 5-NITRO- AND 5-BROMOURACILS [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :316-&

[7] IRREVERSIBLE ENZYME INHIBITORS .79. INHIBITORS OF THYMIDINE PHOSPHORYLASE .V. MODE OF PYRIMIDINE BINDING [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :313-&

[8] ANALOGS OF TETRAHYDROFOLIC ACID .24. FACILE SYNTHETIC ROUTE TO 2-AMINO-5-(3-ANILINOPROPYL)-6-METHYL-4-PYRIMIDINOL TYPE OF FOLIC REDUCTASE + THYMIDYLATE SYNTHETASE INHIBITOR [J].

BAKER, BR ;

SANTI, DV ;

SHAPIRO, HS .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1964, 53 (11) :1317-&

[9] IRREVERSIBLE ENZYME INHIBITORS .76. INHIBITORS OF THYMIDINE PHOSPHORYLASE .2. HYDROPHOBIC BONDING BY 1-SUBSTITUTED URACILS [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :302-&

[10] IRREVERSIBLE ENZYME INHIBITORS .78. INHIBITORS OF THYMIDINE PHOSPHORYLASE .4. HYDROPHOBIC BONDING BY URACILS SUBSTITUTED AT 5 AND 6 POSITIONS [J].

BAKER, BR ;

KAWAZU, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :311-&