EFFECT OF TREATMENT ON FERTILITY AND SEXUAL FUNCTION IN MALES WITH METASTATIC NONSEMINOMATOUS GERM-CELL TUMORS OF TESTIS

被引:21
作者
BRENNER, J [1 ]
VUGRIN, D [1 ]
WHITMORE, WF [1 ]
机构
[1] MEM SLOAN KETTERING CANC CTR, DEPT SURG, UROL SERV, NEW YORK, NY 10021 USA
来源
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS | 1985年 / 8卷 / 02期
关键词
D O I
10.1097/00000421-198504000-00014
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The effects of therapy on the sexual ability and fertility of sixty-seven patients with nonseminomatous germ cell tumors of the testis were analyzed. Ten of 38 patients had subfertile sperm counts before therapy. Normal ejaculation was preserved in only 7/61 patients who underwent retroperitoneal lymph node dissection. In five of these patients, sperm analysis was done after chemotherapy; all had complete azoospermia. An effort to restore ejaculation with imipramine yielded only minimal response in 4/9 patients who received this drug. No major long-term effects on the libido were observed.
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页码:178 / 182
页数:5
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